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[非酒精性脂肪性肝病作为动脉粥样硬化的危险因素]

[Non-alcoholic fatty liver disease as an atherosclerosis risk factor].

作者信息

Roĭtberg G E, Sharkhun O O, Ushakova T I

出版信息

Eksp Klin Gastroenterol. 2010(7):20-4.

Abstract

Currently, along with cardiovascular disease, changes in lipid and carbohydrate metabolism in the syndrome of insulin resistance seen pathology of the liver. The aim of our study was to determine the prognostic significance of nonalcoholic fatty liver disease (NAFLD) to assess the risk of early manifestations of atherosclerotic disease of carotid arteries. The correlation between the presence of NAFLD and signs of early atherosclerosis in the insulin resistance syndrome. The resulting ranked a number of prognostic factors influencing the degree of change in the walls of the carotid arteries, making it possible to construct estimates of individual risk of atherosclerosis development in clinically healthy patients. The clinical significance of the results is the need for more thorough examination of patients with NAFLD to assess risk factors for progression of pathology not only the liver, and cardiovascular disease.

摘要

目前,除心血管疾病外,胰岛素抵抗综合征中脂质和碳水化合物代谢的变化可见于肝脏病变。我们研究的目的是确定非酒精性脂肪性肝病(NAFLD)的预后意义,以评估颈动脉粥样硬化疾病早期表现的风险。NAFLD的存在与胰岛素抵抗综合征中早期动脉粥样硬化体征之间的相关性。由此得出一系列影响颈动脉壁变化程度的预后因素,从而能够构建临床上健康患者动脉粥样硬化发展个体风险的评估。结果的临床意义在于需要对NAFLD患者进行更全面的检查,以评估不仅是肝脏病变,还有心血管疾病进展的危险因素。

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