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[湖南心脑血管疾病死亡的时间趋势及年龄相关特征]

[Time trends and age-related characteristics of cardio-cerebrovascular deaths in Hunan].

作者信息

Ming Hui, Xiang Hui-biao, Huang Min-zhu, Li Guang-chun

机构信息

Public Health School of Central-south University, Changsha, China.

出版信息

Zhonghua Xin Xue Guan Bing Za Zhi. 2010 Jun;38(6):558-61.

Abstract

OBJECTIVE

To investigate the time trends and age-related characteristics of mortality and disease burden for cardiocerebrovascular diseases (CVD) in Hunan, China during three periods (1973-1975, 1990-1992 and 2004-2005).

METHODS

The cardiocerebrovascular death data of Hunan residents were collected by three national retrospective sample surveys of death. Cause-specific mortality, proportion, years of potential life lost (YPLL) and associated indicators were identified in the population of Hunan in above mentioned three periods. Time trends of age-specific mortality rate were assessed by fitting curvilinear regression lines and the increase rates of mortality with age were analyzed in each period.

RESULTS

The standard all-cause mortality of residents in Hunan decreased (chi2 = 189.947, P < 0.001, chi2 = 54.201, P < 0.001; chi2 = 27,396.898, P < 0.001) while the standard mortality for CVD increased (chi2 = 54.201, P < 0.001; chi2 = 27,396.898, P < 0.001) from 1973 to 2005. The age-specific mortality rate for CVD increased with age in all three periods, especially for citizens older than 60 years. There were age stages in each period in which the mortality increase rate was the fastest (10-14 and 15-19 years old in 1973-1975; 10-14, 15-19 and over 80 years old in 1990-1992; 15-19 and over 80 years old in 2004-2005). Exponential regression function (y = b0e(b1x)) can be used for the proper description of age-specific mortality change. The ratio of YPLL for CVD in all death causes showed increase trend (chi2 = 275,630.407, P < 0.001). YPLL rate (YPLLs per 1000) in 1973-1975 was higher than those in 1990-1992 and 2004-2005. YPLL rate was positively correlated with mortality in all periods.

CONCLUSIONS

The mortality for CVD increased with time and aging. People older than 60 years were threatened by CVD mostly. Mortality trend analysis also found higher CVD deaths in people age 15-19 in Hunan residents.

摘要

目的

调查中国湖南省三个时期(1973 - 1975年、1990 - 1992年和2004 - 2005年)心血管疾病(CVD)的死亡率和疾病负担的时间趋势及年龄相关特征。

方法

通过三次全国性死亡回顾性抽样调查收集湖南省居民的心血管疾病死亡数据。确定上述三个时期湖南省人群中特定病因死亡率、比例、潜在寿命损失年数(YPLL)及相关指标。通过拟合曲线回归线评估年龄别死亡率的时间趋势,并分析各时期死亡率随年龄的增长率。

结果

1973年至2005年期间,湖南省居民的标准全因死亡率下降(χ² = 189.947,P < 0.001;χ² = 54.201,P < 0.001;χ² = 27396.898,P < 0.001),而心血管疾病的标准死亡率上升(χ² = 54.201,P < 0.001;χ² = 27396.898,P < 0.001)。在所有三个时期,心血管疾病的年龄别死亡率均随年龄增长而上升,尤其是60岁以上的人群。每个时期都有死亡率上升最快的年龄阶段(1973 - 1975年为10 - 14岁和15 - 19岁;1990 - 1992年为10 - 14岁、15 - 19岁和80岁以上;2004 - 2005年为(15 - 19)岁和80岁以上)。指数回归函数((y = b0e(b1x)))可用于恰当描述年龄别死亡率变化。心血管疾病在所有死亡原因中的YPLL比例呈上升趋势(χ² = 275630.407,P < 0.001)。1973 - 1975年的YPLL率(每1000人年的YPLL数)高于1990 - 1992年和2004 - 2005年。在所有时期,YPLL率与死亡率呈正相关。

结论

心血管疾病的死亡率随时间和年龄增长而上升。60岁以上人群受心血管疾病威胁最大。死亡率趋势分析还发现,湖南省居民中15 - 19岁人群的心血管疾病死亡人数较多。

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