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[1973 - 1994年塞尔维亚(不包括各省份)的死亡率趋势]

[Trends in mortality in Serbia, excluding the provinces, 1973-1994].

作者信息

Vlajinac H, Marinković J, Kocev N, Adanja B, Sipetić S, Pekmezović T, Zivaljević V

机构信息

Institute of Epidemiology, School of Medicine, Belgrade.

出版信息

Srp Arh Celok Lek. 2000 Sep-Oct;128(9-10):309-15.

PMID:11255684
Abstract

The war and break up of former Yugoslavia began in 1991. In May 1992 the United Nations imposed economic sanctions on Serbia and Montenegro which were suspended only in November 1995. The purpose of this study was to assess the effects of the war and UN sanctions on health of the population of Serbia without the provinces of Vojvodina and Kosovo. The period 1973-1994 was studied. Mortality data were derived from unpublished and published materials of the Federal Institute of Statistics [1]. Refugees, who, because of civil war, came to Serbia and Montenegro from other parts of former Yugoslavia, were not counted as a part of the population when mortality rates were calculated. Mortality rates were standardized directly using the "European population" as the standard [2]. The least square method was used to fit mortality rates to different trend curves. Linear trend was used whenever it significantly (p < 0.05) demonstrated the existing mortality rates. To measure the possible effect of the war and sanctions (WAS) on mortality between 1991 and 1994, dummy variable (variable WAS) consisting of 0's and 1's was made to signify the passage from the period before and the period after the beginning of the war and sanctions [3]. Over the period 1991-1994, characterized by the war and UN sanctions, in women aged 25-34, 35-44 and 75-84, total mortality was significantly higher than expected on the basis of the trend for the preceding period (p = 0.006, p = 0.000 and p = 0.015 respectively). The opposite effect was found in the age group 85+ (p = 0.012)/Table 2. Of major causes of death, in age group 25-34, mortality from endocrine diseases increased more rapidly in both sexes (p = 0.000) and mortality from urogenital diseases in women decreased more slowly than expected (p = 0.006). On the other hand, in age group 85+ mortality was significantly lower for cardiovascular diseases in both sexes (p = 0.035 and p = 0.006), for respiratory diseases in men (p = 0.011) and for neoplasms in women (p = 0.006)/Table 4. In addition, in the years 1991 and 1992 the increase in mortality from injuries and poisoning was evident in men aged 15-24, 25-34 and 85+ years (Graph 5). Our results show that over the period 1991-1994 changes in mortality were present in some age groups and were caused by certain groups of diseases. In men, besides mortality of infectious disease which decreased more slowly during 1991-1993 than expected, [4], the main departures were found in the mortality from injuries and poisoning and in mortality from endocrine diseases. The excess of death due to injuries and poisoning in the age group 15-34 can be explained as a direct consequence of the war. There were no military operations on the territory of Serbia, but young men from Serbia were nevertheless engaged in the war in other republics of former Yugoslavia. The outstanding increase in mortality caused by injuries and poisoning in men aged 85+ has two explanations. The first is the fact that suicide rate which was on an average of 86 per 100,000 over the period 1984-1990 rose to 140 per 100,000 during the period 1991-1993. In the year 1994 it fell to 92 per 100,000. Since there were no great differences in percent distribution of suicides among all deaths caused by injuries and poisoning in the two periods (27% in 1984-1990 and 20% in 1991-1993), it is clear that the rise of suicidal rate cannot be the only explanation for increased mortality from injuries and poisoning. In a situation when medical services were badly overextended (lack of medical equipment and proper maintenance of the existing equipment, lack of drugs and other medical inputs, a large number of wounded coming from Bosnia as well as numerous refugees) [5, 6], priority had to be given to younger age groups. Higher mortality due to endocrine diseases in men and women aged 25-34 years and higher mortality due to urogenital diseases in women of the same ages can be most probably attributed to poor medical supplies. Although formally excluded from the international economic blockade medical supplies were in practice badly affected by the fact that the dinar was rendered almost worthless and the Ministry of Health could no longer pay the medical inputs. In addition, bureaucratic hurdles of getting clearance from the UN added months of delay and made foreign companies unwilling to trade [5, 7]. The supply and distribution of drugs within the country was also irregular because communication lines were cut and local companies were not prepared to risk distributing drugs that nobody could pay for [7]. Higher than expected mortality in women aged 25-44 over the period 1991-1994 could be probably explained by their higher vulnerability (period of fertility) and the fact that the main burden of family survival was on them, so they had no time to think and to take care of their health. (ABSTRACT TRUNCATED)

摘要

前南斯拉夫的战争与解体始于1991年。1992年5月,联合国对塞尔维亚和黑山实施经济制裁,制裁直到1995年11月才暂停。本研究的目的是评估战争和联合国制裁对塞尔维亚(不包括伏伊伏丁那省和科索沃省)人口健康的影响。研究时间段为1973 - 1994年。死亡率数据来自联邦统计局未发表和已发表的资料[1]。在计算死亡率时,因内战从前南斯拉夫其他地区来到塞尔维亚和黑山的难民未被计入人口。死亡率直接以“欧洲人口”为标准进行标准化[2]。使用最小二乘法将死亡率拟合到不同的趋势曲线。只要线性趋势能显著(p < 0.05)显示现有死亡率,就采用线性趋势。为衡量1991年至1994年战争和制裁(WAS)对死亡率的可能影响,创建了由0和1组成的虚拟变量(变量WAS),以表示战争和制裁开始前后的时间段[3]。在以战争和联合国制裁为特征的1991 - 1994年期间,25 - 34岁、35 - 44岁和75 - 84岁的女性总死亡率显著高于根据前一时期趋势预期的水平(分别为p = 0.006、p = 0.000和p = 0.015)。在85岁及以上年龄组发现了相反的效果(p = 0.012)/表2。在主要死因方面,在25 - 34岁年龄组,内分泌疾病导致的男女死亡率上升更快(p = 0.000),女性泌尿生殖系统疾病导致的死亡率下降比预期更慢(p = 0.006)。另一方面,在85岁及以上年龄组,男女心血管疾病导致的死亡率显著降低(p = 0.035和p = 0.006),男性呼吸系统疾病导致的死亡率降低(p = 0.011),女性肿瘤导致的死亡率降低(p = 0.006)/表4。此外,在1991年和1992年,15 - 24岁、25 - 34岁和85岁及以上男性因伤害和中毒导致的死亡率上升明显(图5)。我们的结果表明,在1991 - 1994年期间,某些年龄组的死亡率出现了变化,并且是由某些疾病组引起的。在男性中,除了1991 - 1993年期间传染病死亡率下降比预期更慢外,[4]主要差异在于伤害和中毒导致的死亡率以及内分泌疾病导致的死亡率。15 - 34岁年龄组因伤害和中毒导致的死亡过多可解释为战争的直接后果。塞尔维亚领土上没有军事行动,但塞尔维亚的年轻人却参与了前南斯拉夫其他共和国的战争。85岁及以上男性因伤害和中毒导致的死亡率显著上升有两种解释。第一个原因是,1984 - 1990年期间自杀率平均为每10万人86例,在1991 - 1993年期间升至每10万人140例。1994年降至每10万人92例。由于两个时期自杀在所有伤害和中毒导致的死亡中所占百分比分布没有太大差异(1984 - 1990年为27%,1991 - 1993年为20%),显然自杀率上升不可能是伤害和中毒导致死亡率上升的唯一解释。在医疗服务严重超负荷的情况下(缺乏医疗设备以及对现有设备的妥善维护、缺乏药品和其他医疗投入、大量来自波斯尼亚的伤员以及众多难民)[5, 6],必须优先照顾年轻年龄组。25 - 34岁男女因内分泌疾病导致的较高死亡率以及同一年龄段女性因泌尿生殖系统疾病导致的较高死亡率很可能归因于医疗用品供应不足。尽管在形式上被排除在国际经济封锁之外,但医疗用品实际上受到了严重影响,因为第纳尔几乎一文不值,卫生部再也无法支付医疗投入。此外,从联合国获得许可的官僚障碍增加了数月的延迟,使得外国公司不愿进行贸易[5, 7]。国内药品的供应和分配也不规律,因为通信线路被切断,当地公司不愿意冒险分发无人能够支付费用的药品[7]。1991 - 1994年期间25 - 44岁女性高于预期的死亡率可能可以解释为她们更高的脆弱性(生育期)以及家庭生存的主要负担落在她们身上,所以她们没有时间考虑和照顾自己的健康。(摘要截断)

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