Noskov V B, Larina I M, Nichiporuk I A, Pastushkova L Kh, Vasil'eva G Iu
Aviakosm Ekolog Med. 2010 May-Jun;44(3):32-7.
Effects of synthesized desmopressin, analog of antidiuretic hormone, and water-salt supplement on the renal function and orthostatic stability were studied in 6 normal male subjects after 12-hr. head-down tilt (12 degrees). The combination of water-salt homeostasis normalizing methods was effective in retaining excessive liquid and salts. Moreover, tolerance of the standard 20-min. passive standing test improved significantly. Hence, it was demonstrated that intake of synthetic vasopressin analog combined with WSS counteracted hypohydration of organism due to HDT and improved orthostatic tolerance.
在6名正常男性受试者经历12小时头低位倾斜（12度）后，研究了合成去氨加压素（抗利尿激素类似物）和水盐补充对肾功能及体位稳定性的影响。水盐平衡调节方法的联合应用在保留过多液体和盐分方面是有效的。此外，标准20分钟被动站立试验的耐受性显著改善。因此，已证明合成血管加压素类似物与水盐补充剂联合摄入可抵消头低位倾斜导致的机体脱水并改善体位耐受性。
