Department of Ophthalmology, China Medical University Hospital, Taichung, Taiwan.
Ocul Immunol Inflamm. 2011 Feb;19(1):69-71. doi: 10.3109/09273948.2010.519851. Epub 2010 Oct 31.
To describe an atypical case of cytomegalovirus (CMV) endotheliitis in a 74-year-old man who presented with chronic corneal edema without keratic precipitates (KPs) and intraocular pressure (IOP) elevation.
Case report.
A complete ophthalmologic examination was performed. Polymerase chain reaction was used to test for herpes simplex virus, varicella zoster virus, and CMV DNA in aqueous humor samples to rule out viral endotheliitis.
Severe bullous keratopathy was found in the temporal part of the cornea without KPs or elevated IOP. CMV DNA was detected. Corneal edema subsided with oral valganciclovior.
CMV endotheliitis may present as corneal edema that lacks typical features, such as KPs or elevated IOP.
描述一例 74 岁男性出现慢性角膜水肿而无角膜后沉淀物(KP)和眼内压(IOP)升高的巨细胞病毒(CMV)血管内皮炎的不典型病例。
病例报告。
进行全面的眼科检查。聚合酶链反应用于检测房水样本中的单纯疱疹病毒、水痘带状疱疹病毒和 CMV DNA,以排除病毒性血管内皮炎。
在角膜颞部发现严重的大疱性角膜病变,无 KP 或 IOP 升高。检测到 CMV DNA。口服缬更昔洛韦后角膜水肿消退。
CMV 血管内皮炎可表现为缺乏典型特征(如 KP 或 IOP 升高)的角膜水肿。