Department of Ophthalmology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, China.
Chin Med J (Engl). 2010 Oct;123(19):2662-5.
The blood supply to the eye comes from the retinal central vascular system of the ophthalmic artery and the ciliary vascular system. The ophthalmic artery stems from the ipsilateral internal carotid artery. If occlusion or stenosis occurs in the carotid artery, the blood perfusion to the ophthalmic artery becomes insufficient, leading to signs and symptoms of anterior and posterior ocular ischemia. The objective of this study was to evaluate the clinical characteristics and risk factors of ocular ischemic diseases caused by carotid artery stenosis.
This study was a retrospective review of 145 patients with carotid artery stenosis. Fifty-eight patients who had symptoms of ocular ischemic disease caused by carotid artery stenosis formed group A and the other 87 patients who only had carotid artery stenosis formed group B. We analyzed the causes and course of disease, and relative risk factors, by comparing the two groups.
The degree of carotid artery stenosis in group A was higher than that in group B. And group A had a greater decrease of ophthalmic artery flow. Male, hypertension, hyperlipidemia, and smoking were significantly related to carotid artery stenosis. Amaurosis fugax was the most common ocular symptom in group A. The ocular ischemic diseases mainly included ischemic optic neuropathy, central/branch retinal artery occlusion, ophthalmoplegia externa, and ocular ischemic syndrome.
Carotid artery stenosis correlates with ocular ischemic diseases. Ophthalmologists must observe for ocular symptoms, which were the onset symptoms in some patients.
眼部的血液供应来自眼动脉的视网膜中央血管系统和睫状血管系统。眼动脉源自同侧颈内动脉。如果颈内动脉发生闭塞或狭窄，眼动脉的血液灌注不足，导致前、后眼部缺血的征象和症状。本研究的目的是评估颈动脉狭窄引起的眼部缺血性疾病的临床特征和危险因素。
这是一项对 145 例颈动脉狭窄患者的回顾性研究。58 例因颈动脉狭窄引起眼部缺血性疾病症状的患者为 A 组，另 87 例仅存在颈动脉狭窄的患者为 B 组。通过比较两组，分析了病因和病程以及相关危险因素。
A 组的颈动脉狭窄程度高于 B 组，A 组眼动脉血流明显减少。男性、高血压、高血脂和吸烟与颈动脉狭窄显著相关。一过性黑矇是 A 组最常见的眼部症状。眼部缺血性疾病主要包括缺血性视神经病变、中心/分支视网膜动脉阻塞、外展神经麻痹和眼部缺血综合征。
颈动脉狭窄与眼部缺血性疾病相关。眼科医生必须观察眼部症状，因为这些症状是一些患者的首发症状。
