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尼日利亚毒蛇咬伤的院前救治效果。

The effect of pre-hospital care for venomous snake bite on outcome in Nigeria.

机构信息

Department of Family Medicine, Aminu Kano Teaching Hospital, PMB 3452 Kano, Nigeria.

出版信息

Trans R Soc Trop Med Hyg. 2011 Feb;105(2):95-101. doi: 10.1016/j.trstmh.2010.09.005. Epub 2010 Oct 28.

Abstract

We studied pre-hospital practices of 72 consecutive snake bite victims at a hospital in north-central Nigeria. The primary outcome assessed was death or disability at hospital discharge. Victims were predominantly male farmers, and in 54 cases (75%) the snake was identified as a carpet viper (Echis ocellatus), with the remainder unidentified. Most subjects (58, 81%) attempted at least one first aid measure after the bite, including tourniquet application (53, 74%), application (15, 21%) or ingestion (10, 14%) of traditional concoctions, bite site incision (8, 11%), black stone application (4, 5.6%), and suction (3, 4.2%). The majority (44, 61%) presented late (after 4 hours). Most (53, 74%) had full recovery at hospital discharge. Three deaths (4.2%) and thirteen (18%) disabilities (mainly tissue necrosis) occurred. The use of any first aid was associated with a longer hospital stay than no use (4.6 ± 2.0 days versus 3.6 ± 2.7 days, respectively, P = 0.02). The antivenom requirement was greater in subjects who had used a tourniquet (P = 0.03) and in those who presented late (P = 0.02). Topical application (Odds Ratio 15, 95% CI 1.4-708) or ingestion of traditional concoctions (OR 20, 95% CI 1.4-963) were associated with increased risk of death or disability. Ingestion and application of concoctions were associated with a longer time interval before presentation, a higher cost of hospitalization, and an increased risk of wound infection.

摘要

我们研究了尼日利亚中北部一家医院的 72 例连续蛇咬伤患者的院前治疗情况。主要结局评估是出院时的死亡或残疾。受害者主要是男性农民,54 例(75%)蛇被确认为地毯毒蛇(Echis ocellatus),其余无法识别。大多数患者(58,81%)在咬伤后至少采取了一种急救措施,包括止血带应用(53,74%)、应用(15,21%)或摄入(10,14%)传统制剂、咬伤部位切开(8,11%)、黑石应用(4,5.6%)和抽吸(3,4.2%)。大多数(44,61%)就诊较晚(4 小时后)。大多数(53,74%)在出院时完全康复。有 3 例死亡(4.2%)和 13 例残疾(主要是组织坏死)。与未使用任何急救措施相比,使用任何急救措施的患者住院时间更长(分别为 4.6 ± 2.0 天和 3.6 ± 2.7 天,P = 0.02)。使用止血带的患者(P = 0.03)和就诊较晚的患者(P = 0.02)需要使用抗蛇毒血清的可能性更大。局部应用(优势比 15,95%CI 1.4-708)或摄入传统制剂(OR 20,95%CI 1.4-963)与死亡或残疾的风险增加相关。摄入和应用制剂与就诊前时间间隔延长、住院费用增加和伤口感染风险增加有关。

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