Institut Clínic d'Oftalmologia (ICOF), Hospital Clínic I Provincial, Barcelona, Spain.
Surv Ophthalmol. 2011 Mar-Apr;56(2):173-7. doi: 10.1016/j.survophthal.2010.06.001. Epub 2010 Oct 30.
A 63-year-old woman developed consecutive visual loss in the presence of chronic renal failure on hemodyalisis, arterial hypertension, and pulmonary hypertension treated with sildenafil. Temporal artery biopsy was negative for giant cell arteritis. Bilateral, consecutive non-arteritic ischemic optic neuropathy was diagnosed. The implications and potential risk of sildenafil use in women are discussed.
一位 63 岁女性在接受血液透析治疗慢性肾衰竭、动脉高血压和肺动脉高压期间出现连续视力丧失,同时服用西地那非。颞动脉活检排除巨细胞动脉炎。诊断为双侧、连续的非动脉炎性缺血性视神经病变。讨论了西地那非在女性中的使用意义和潜在风险。