Bhatt-Mehta Varsha, Donn Steven M
College of Pharmacy, University of Michigan Health System, Ann Arbor, MI 48109-5254, USA.
Expert Rev Clin Pharmacol. 2014 Jul;7(4):393-5. doi: 10.1586/17512433.2014.922867. Epub 2014 May 28.
Sildenafil, a phospohodiesterase-5 inhibitor, is widely used to treat pulmonary hypertension in infants with bronchopulmonary dysplasia despite a lack of evidence to support either safety or efficacy and US FDA advice against its use.
西地那非，一种磷酸二酯酶-5抑制剂，尽管缺乏支持其安全性或有效性的证据，且美国食品药品监督管理局（FDA）也建议不要使用，但仍被广泛用于治疗支气管肺发育不良婴儿的肺动脉高压。
