Tan Neil C W, Mellor Tim, Brennan Peter A, Puxeddu Roberto
Department of Otorhinolaryngology, Head and Neck Surgery, Queen Alexandra Hospital, Portsmouth, Hampshire, PO6 3LY, UK.
Br J Oral Maxillofac Surg. 2011 Sep;49(6):488-90. doi: 10.1016/j.bjoms.2010.09.001. Epub 2010 Oct 30.
Erythroplakia is an epithelial lesion that holds the highest risk of showing severe dysplasia or microinvasive carcinoma. The gold standard treatment is total excision to obtain a complete histopathological diagnosis. Traditionally this has been done by illumination of the lesion with white light, and resection with adequate margins. The difficulty with erythroplakia is that margins can be hard to delineate precisely, and even severe dysplasia can be seen with only subtle changes in the surface mucosa. Narrow band imaging is a novel technique that enhances the diagnostic potential of endoscopy. It highlights abnormalities in the superficial vasculature, which means that lesions such as oral erythroplakia can be identified more easily. We report its use in the identification of the full extent of lesions, and show its intraoperative advantages in obtaining resection margins free from disease.
红斑是一种上皮病变，具有发展为重度发育异常或微浸润癌的最高风险。金标准治疗方法是完全切除以获得完整的组织病理学诊断。传统上，这是通过白光照射病变部位并进行足够切缘的切除来完成的。红斑的难点在于切缘很难精确界定，而且即使是重度发育异常在表面黏膜上也可能仅表现为细微变化。窄带成像技术是一种能增强内镜诊断潜力的新技术。它能突出浅表血管系统的异常，这意味着像口腔红斑这样的病变更容易被识别。我们报告了其在确定病变范围方面的应用，并展示了其在术中获得无病变切缘方面的优势。
