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球囊椎体后凸成形术增强短节段后路固定治疗胸腰椎骨质疏松性骨折合并神经功能缺损:与单纯后路手术和前路手术的比较

Vertebroplasty-augmented short-segment posterior fixation of osteoporotic vertebral collapse with neurological deficit in the thoracolumbar spine: comparisons with posterior surgery without vertebroplasty and anterior surgery.

机构信息

Department of Orthopaedics and Rehabilitation Medicine, Fukui University Faculty of Medical Sciences, Fukui, Japan.

出版信息

J Neurosurg Spine. 2010 Nov;13(5):612-21. doi: 10.3171/2010.5.SPINE09813.

Abstract

OBJECT

The surgical approach and treatment of thoracolumbar osteoporotic vertebral collapse with neurological deficit have not been documented in detail. Anterior surgery provides good decompression and solid fusion, but the surgery-related risk is relatively higher than that associated with the posterior approach. In posterior surgery, the major problem after posterior correction and instrumentation is failure to support the anterior spinal column, leading to loss of correction of kyphosis. The aim of this study was to evaluate the efficacy of reinforcing short-segment posterior fixation with vertebroplasty and to compare the outcome with those of posterior surgery without vertebroplasty and anterior surgery, retrospectively.

METHODS

The authors studied 83 patients who underwent surgical treatment for a single thoracolumbar osteoporotic vertebral collapse with neurological deficit. Twenty-eight patients treated by posterior surgery combined with vertebroplasty (Group A), 25 patients treated by posterior surgery without vertebroplasty (Group B), and 30 patients treated by anterior surgery (Group C) were followed up for a mean postoperative period of 4.4 years. Neurological outcome, visual analog scale pain score, and radiographic results were compared in the 3 groups.

RESULTS

Postoperative (4-6 weeks) and follow-up neurological outcome and visual analog scale scores were not significantly different among the 3 groups. Postoperative kyphotic angle was significantly reduced in Group B compared with Group C (p = 0.007), whereas the kyphotic angle was not significantly different among the 3 groups at follow-up. The mean ± SD loss of correction at follow-up was 4.6° ± 4.5°, 8.6° ± 6.2°, and 4.5° ± 5.9° in Groups A, B, and C, respectively. The correction loss at follow-up in Group B was significantly higher compared with Groups A and C (p = 0.0171 and p = 0.0180, respectively).

CONCLUSIONS

The results suggest that additional reinforcement with vertebroplasty reduces the kyphotic loss and instrumentation failure, compared with patients without the reinforcement of vertebroplasty. Vertebroplasty-augmented short-segment fixation seems to offer immediate spinal stability in patients with thoracolumbar osteoporotic vertebral collapse; the effect seems equivalent to that of anterior reconstruction.

摘要

目的

胸腰椎骨质疏松性椎体塌陷伴神经功能缺损的手术入路和治疗方法尚未详细记录。前路手术可提供良好的减压和固定融合,但手术相关风险相对高于后路手术。后路手术中,后路矫正和内固定后主要问题是不能支撑前脊柱柱,导致后凸畸形矫正丢失。本研究旨在评估经皮椎体后凸成形术强化短节段后路固定的疗效,并与后路手术不伴经皮椎体后凸成形术和前路手术的结果进行比较,回顾性研究。

方法

作者研究了 83 例接受单一胸腰椎骨质疏松性椎体塌陷伴神经功能缺损手术治疗的患者。28 例后路手术联合经皮椎体后凸成形术(A 组)、25 例后路手术不伴经皮椎体后凸成形术(B 组)和 30 例前路手术(C 组)患者平均随访 4.4 年。比较三组患者的神经功能、视觉模拟量表疼痛评分和影像学结果。

结果

术后(4-6 周)和随访时神经功能和视觉模拟量表评分三组间无显著性差异。B 组术后后凸角较 C 组明显减小(p = 0.007),而三组随访时后凸角无显著差异。随访时平均(±SD)矫正丢失分别为 A、B、C 组 4.6°±4.5°、8.6°±6.2°和 4.5°±5.9°。B 组随访时矫正丢失明显高于 A 组和 C 组(p = 0.0171 和 p = 0.0180)。

结论

结果表明,与未行经皮椎体后凸成形术强化的患者相比,附加经皮椎体后凸成形术强化可减少后凸丢失和器械失败。经皮椎体后凸成形术强化短节段固定似乎可在胸腰椎骨质疏松性椎体塌陷患者中即刻提供脊柱稳定性,其效果与前路重建相当。

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