Psychology Department, East Carolina University, Greenville, NC 27858, USA.
J Psychosom Obstet Gynaecol. 2010 Dec;31(4):219-28. doi: 10.3109/0167482X.2010.518776. Epub 2010 Nov 2.
The objective of this study was to evaluate the relationship between psychosocial stress in pregnancy and negative perinatal outcomes and to identify key moderators of this relationship. To evaluate this relationship, a meta-analytic review was conducted of studies that prospectively assessed the relationship between psychosocial stress in pregnancy and perinatal outcomes. A total of 35 studies, written or published between 1991 and 2009, involving 31,323 women were located. The overall association between psychosocial stress and negative perinatal outcomes was significant, but negligibly small in size (r (35) = -0.04, CI = -0.08, -0.01). Examining specific perinatal outcomes, only the associations with neonatal weight (r (14) = -0.07, CI = -0.03, -0.01) and risk for low birth weight (r (5) = 0.07, CI = 0.03, 0.10) were statistically significant, but again, very small. Results support that psychosocial stress explains a negligible to very small amount of the variability in perinatal outcomes. Future research should focus on identifying other psychosocial and lifestyle variables that alone or in interaction with other factors explain larger amounts of the variability in perinatal outcomes. Future research should also examine whether psychosocial stress increases risk for negative outcomes in combination with other biomedical and psychosocial risk factors.
这项研究的目的是评估孕期心理社会压力与不良围产结局之间的关系，并确定该关系的关键调节因素。为了评估这种关系，对前瞻性评估孕期心理社会压力与围产结局之间关系的研究进行了荟萃分析。共找到 35 项研究，这些研究于 1991 年至 2009 年间发表，共涉及 31323 名妇女。孕期心理社会压力与不良围产结局之间的总体关联具有统计学意义，但关联程度很小（r(35)=-0.04，CI=-0.08，-0.01）。在考察特定的围产结局时，只有与新生儿体重（r(14)=-0.07，CI=-0.03，-0.01）和低出生体重风险（r(5)=0.07，CI=-0.03，0.10）相关的关联具有统计学意义，但关联程度也很小。研究结果表明，心理社会压力对围产结局的变异性的解释程度可忽略不计或非常小。未来的研究应集中于确定其他心理社会和生活方式变量，这些变量单独或与其他因素共同作用，可以更好地解释围产结局的变异性。未来的研究还应检验心理社会压力是否与其他生物医学和心理社会危险因素一起增加不良结局的风险。
