Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Charité-Universitätsmedizin Berlin, Germany.
J Child Psychol Psychiatry. 2011 Jun;52(6):686-95. doi: 10.1111/j.1469-7610.2010.02322.x. Epub 2010 Oct 11.
Recently, a highly heritable behavioral phenotype of simultaneous deviance on the Anxious/Depressed, Attention Problems, and Aggressive Behavior syndrome scales has been identified on the Child Behavior Checklist (CBCL-Dysregulation Profile, CBCL-DP). This study aims to investigate psychosocial adversity and impairment of the CBCL-DP.
A total of 9024 patients aged 4-18 years were assessed using the CBCL, and the axes V and VI of ICD-10.
ANOVA revealed significant differences regarding psychosocial adversity and impairment between patients with CBCL-DP phenotype and the clinical control group, patients with attention problems, and patients with attention problems and additional anxious/depressed symptoms as assessed by the CBCL. Patients with CBCL-DP showed significant psychosocial adversity and impairment. However, in most cases patients with aggressive behavior showed equal psychosocial adversity as patients with CBCL-DP.
Findings suggest the CBCL-DP phenotype to be associated with significant psychosocial adversity and impairment either as a cause or an effect of the syndrome. Clinicians should carefully address psychosocial adversity and impairment with particular attention to the adversity and impairment of adolescents with CBCL-DP.
最近，在儿童行为检查表（CBCL-失调特征，CBCL-DP）上发现了一种同时在焦虑/抑郁、注意力问题和攻击性行为综合征量表上表现出高度遗传性行为表型的特征。本研究旨在探讨 CBCL-DP 的心理社会逆境和损伤。
共有 9024 名 4-18 岁的患者使用 CBCL 和 ICD-10 的轴 V 和 VI 进行评估。
方差分析显示，CBCL-DP 表型患者与临床对照组、CBCL 评估的注意力问题患者和注意力问题及附加焦虑/抑郁症状患者之间在心理社会逆境和损伤方面存在显著差异。CBCL-DP 患者表现出明显的心理社会逆境和损伤。然而，在大多数情况下，具有攻击性行为的患者与具有 CBCL-DP 的患者具有相同的心理社会逆境。
研究结果表明，CBCL-DP 表型与显著的心理社会逆境和损伤有关，无论是作为该综合征的原因还是结果。临床医生应仔细处理心理社会逆境和损伤问题，特别注意具有 CBCL-DP 的青少年的逆境和损伤。
