Periodontology Unit, Department of Clinical Research, UCL Eastman Dental Institute, London, UK.
Clin Oral Implants Res. 2011 Jan;22(1):38-46. doi: 10.1111/j.1600-0501.2010.01988.x. Epub 2010 Oct 6.
to evaluate the effect of the timing of loading on bone-to-implant contact (BIC) following immediate placement of implants with a hydrophilic sandblasted, large-grit and acid-etched surface (modSLA) into fresh extraction sockets in a minipig model.
six minipigs were used in this study. In each hemi-mandible, two conical shape implants (TE, Straumann implants) with a hydrophilic surface (modSLA) were placed in fresh extraction sockets. In one side of the mandible (control), two implants were immediately placed in fresh extraction sockets. The implants were loaded after 4 weeks of healing. At the contralateral side (test), two implants were immediately placed and loaded. After 8 weeks of healing, the animals were sacrificed and histologically analysed.
during the experimental period, no implants were lost and all of them presented to be osseointegrated. The percentage of BIC was similar in both groups: 66.1% and 65.1% for the control and test group, respectively. Furthermore, the distance from the shoulder of the implant to bone crest and the distance from the shoulder to the first BIC were similar in both groups.
immediate implant placement and loading showed similar BIC with immediate placement and delayed loading when implants with a modSLA surface were used. Both procedures showed similar buccal bone crest levels, which presented some resorption irrespective of the treatment modality.
评估亲水喷砂大颗粒酸蚀表面（modSLA）种植体即刻植入新鲜拔牙窝后，加载时机对种植体骨结合率（BIC）的影响。
本研究使用了 6 只小型猪。在每只半下颌骨中，将 2 个具有亲水表面（modSLA）的锥形形状种植体（TE，Straumann 种植体）放置在新鲜拔牙窝中。在下颌骨的一侧（对照组），2 个种植体立即放置在新鲜拔牙窝中。愈合 4 周后进行加载。在对侧（实验组），2 个种植体立即放置并加载。愈合 8 周后，处死动物并进行组织学分析。
在实验期间，没有种植体脱落，所有种植体均表现出骨整合。两组的 BIC 百分比相似：对照组为 66.1%，实验组为 65.1%。此外，两组种植体肩台到牙槽嵴的距离和种植体肩台到第一次 BIC 的距离相似。
当使用 modSLA 表面的种植体时，即刻种植体植入和即刻加载与即刻植入和延迟加载具有相似的 BIC。两种方法的颊侧牙槽嵴水平相似，均出现了一些吸收，与治疗方式无关。
