Department of Periodontics, Samsung Medical Center, The Institute of Oral Health Science, Sungkyunkwan University School of Medicine, Gangnam-gu, Seoul, Korea.
Clin Oral Implants Res. 2011 Mar;22(3):289-94. doi: 10.1111/j.1600-0501.2010.01995.x. Epub 2010 Oct 6.
For successful implant treatment in the esthetic area, stable hard tissue and soft tissue are very important. At the buccal side without buccal bone defects, prophylactic guided bone regeneration (GBR) with bone substitute was frequently used for achieving thick buccal bone. The aim of this study was to evaluate the effect of GBR using a non-resorbable membrane in an immediate implant site without bone defects.
Immediate implants were placed into the mandibles of four mongrel dogs. In the experimental group (TM group), a non-resorbable membrane was placed and fixed onto the buccal bone plate around the implant. In the control group, the implants were placed without membrane coverage. After 12 weeks, the dogs were sacrificed and histological specimens were prepared. The vertical distances from the smooth-rough surface interface (SRI) to the gingiva, the first-bone contact, and the bone crest were measured on the buccal and lingual sides. The horizontal thicknesses of the gingiva and bone at 0, 1, 2, and 3 mm below the SRI were measured.
In the TM group, first-bone contact on the buccal side was more coronally positioned approximately 0.8 mm than the control group (P=0.041). The buccal bone thickness of the TM group was well preserved and there was no difference between the buccal and lingual sides. Comparing the control group, implants of the TM group had 1 mm thicker buccal bone (P=0.0051 at bone 1 mm level, P=0.002 at bone 2 mm level). In the control group, buccal bone loss was observed and buccal bone was about 1 mm thinner than the lingual bone (P<0.05).
GBR with a non-resorbable membrane and no bone graft substitute could help to preserve buccal bone thickness on the immediate implant site without defects.
在美学区域进行成功的种植治疗，稳定的硬组织和软组织非常重要。在颊侧无颊骨缺损的情况下，常采用预防性引导骨再生（GBR）并用骨替代物来获得较厚的颊骨。本研究的目的是评估在无骨缺损的即刻种植部位使用不可吸收膜进行 GBR 的效果。
将即刻种植体植入四只杂种犬的下颌骨。在实验组（TM 组）中，将不可吸收膜放置并固定在种植体周围的颊骨板上。在对照组中，种植体放置时不覆盖膜。12 周后，处死犬并制备组织学标本。在颊侧和舌侧测量从光滑-粗糙表面界面（SRI）到牙龈、第一骨接触和牙槽嵴的垂直距离。在 SRI 下方 0、1、2 和 3mm 处测量牙龈和骨的水平厚度。
在 TM 组中，颊侧的第一骨接触比对照组更向冠方约 0.8mm（P=0.041）。TM 组的颊骨厚度得到很好的保留，颊侧和舌侧之间没有差异。与对照组相比，TM 组的种植体有 1mm 更厚的颊骨（在骨 1mm 水平时 P=0.0051，在骨 2mm 水平时 P=0.002）。在对照组中，观察到颊骨吸收，颊骨比舌骨薄约 1mm（P<0.05）。
在无缺陷的即刻种植部位使用不可吸收膜和无骨移植替代物的 GBR 有助于保持颊骨厚度。
