UNESP - Faculty of Dentistry of Araçatuba, São Paulo State University, Brazil.
Clin Oral Implants Res. 2011 May;22(5):512-7. doi: 10.1111/j.1600-0501.2010.02040.x. Epub 2010 Dec 9.
To evaluate the influence of magnesium-enriched hydroxyapatite (MHA) (SintLife(®)) on bone contour preservation and osseointegration at implants placed immediately into extraction sockets.
In the mandibular pre-molar region, implants were installed immediately into extraction sockets of six Labrador dogs. MHA was placed at test sites, while the control sites did not receive augmentation materials. Implants were intended to heal in a submerged mode. After 4 months of healing, the animals were sacrificed, and ground sections were obtained for histomorphometric evaluation.
After 4 months of healing, one control implant was not integrated leaving n=5 test and control implants for evaluation. Both at the test and the control sites, bone resorption occurred. While the most coronal bone-to-implant contact was similar between test and control sites, the alveolar bony crest outline was maintained to a higher degree at the buccal aspect of the test sites (loss: 0.7 mm) compared with the control sites (loss: 1.2 mm), even though this difference did not reach statistical significance.
The use of MHA to fill the defect around implants placed into the alveolus immediately after tooth extraction did not contribute significantly to the maintenance of the contours of the buccal alveolar bone crest.
评估富含镁的羟基磷灰石（MHA）（SintLife(®)）对即刻植入拔牙窝的种植体骨轮廓维持和骨整合的影响。
在下颌前磨牙区，将种植体即刻植入六只拉布拉多犬的拔牙窝中。在试验部位放置 MHA，而对照部位不接受增强材料。种植体采用淹没式愈合。愈合 4 个月后，处死动物，获得研磨截面进行组织形态计量学评估。
愈合 4 个月后，一个对照种植体未整合，n=5 个试验和对照种植体用于评估。在试验和对照部位均发生了骨吸收。虽然最冠方的骨-种植体接触在试验和对照部位相似，但试验部位颊侧的牙槽骨嵴轮廓保持程度更高（丧失：0.7mm），与对照部位（丧失：1.2mm）相比，尽管这种差异没有达到统计学意义。
在拔牙后即刻将 MHA 填充到植入物周围的缺损中，对维持颊侧牙槽骨嵴轮廓没有显著贡献。
