Department of Dermatology, Venereology and Allergology, University Medical Center Mannheim, Ruprecht-Karls-University of Heidelberg, Mannheim, Germany.
J Eur Acad Dermatol Venereol. 2011 Jul;25(7):788-93. doi: 10.1111/j.1468-3083.2010.03863.x. Epub 2010 Oct 6.
The reconstruction of deep facial wounds in oncological surgery is challenging. Especially for elderly multimorbid patients, a rapid procedure with acceptable aesthetic and reliable functional outcome is required. Recently, a new single layer skin substitute was developed. Integra® dermal regeneration template single layer (IDRT-SL) allows one-stage surgery in combination with split thickness skin grafting. However, no study has yet analysed the efficiency of IDRT-SL treatment.
To evaluate applicability and efficiency of the IDRT-SL treatment in combination with split thickness skin grafting for a one-step closure of deep facial surgical wounds in elderly multimorbid patients.
PATIENTS/METHODS: This prospective study analysed the functional and aesthetic outcome after reconstruction with an IDRT-SL template and an immediate split thickness skin graft in the face (80±3 years; >3 concomitant diseases).
Nine tumours, four basal cell carcinoma, two lentigo maligna, one spinal cell carcinoma, one lentigo maligna melanoma and one Bowen carcinoma were resected. Five defects were located on the nose and four on the cheek. The mean defect size was 11±3 cm2. All but one graft were taken completely without any complication. One patient suffered from a partial graft loss (30%). All defects showed significant shrinkage of 61±4%.
One-stage reconstruction with a combination of IDRT-SL and split thickness skin grafting is an elegant, easy and rapid method to treat deep skin defects. The take rates, functional and early cosmetic outcome are promising. This new method should be considered for selected cases of elderly multimorbid patients with deep facial wounds.
在肿瘤外科中,深部面创伤的重建颇具挑战性。对于老年多病患者,需要一种快速的手术方法,以获得可接受的美容效果和可靠的功能结果。最近,一种新型的单层皮肤替代物被开发出来。Integra®真皮再生模板单层(IDRT-SL)允许与断层皮片移植相结合的一期手术。然而,目前尚无研究分析 IDRT-SL 治疗的效率。
评估 IDRT-SL 联合断层皮片移植在老年多病患者深部面手术伤口一期闭合中的应用和效率。
患者/方法:本前瞻性研究分析了 9 例肿瘤(4 例基底细胞癌、2 例恶性雀斑样痣、1 例脊髓细胞癌、1 例恶性雀斑样痣黑素瘤和 1 例 Bowen 癌)患者的功能和美容结果,这些患者接受了 IDRT-SL 模板和即刻断层皮片移植的重建(年龄 80±3 岁;≥3 种合并症)。
5 个缺陷位于鼻子上,4 个位于脸颊上。平均缺陷大小为 11±3cm2。除 1 例外,所有皮片均完全移植,无任何并发症。1 例患者发生部分皮片丢失(30%)。所有缺损均有显著的 61±4%的缩小。
IDRT-SL 联合断层皮片移植的一期重建是一种优雅、简单、快速的治疗深部皮肤缺损的方法。皮片成活率、功能和早期美容效果令人满意。对于老年多病患者深部面创伤,这种新方法应考虑用于选择病例。