Department of Dermatology, Gulhane School of Medicine, Keçiören, Ankara, Turkey.
Dermatol Surg. 2010 Dec;36(12):1973-8. doi: 10.1111/j.1524-4725.2010.01770.x. Epub 2010 Oct 11.
Xanthelasma palpebrarum (XP) is the most common form of xanthoma, which is mostly located on the eyelids. Various treatment options are available, with certain limitations, and none of them is satisfactory.
To offer another treatment option (low-voltage radiofrequency (RF)) and to evaluate its efficacy in XP.
Fifteen patients were included in the study. The patients were examined before treatment, at the end of treatment, and 5 months later at a follow-up visit. Improvement was judged according to clinical examination by comparing before and after photographs. Electrodes from a dual-frequency 4.0-MHz RF machine were applied superficially to the lesions. The clinical scores were calculated using a 5-point scale (0=no result, 0-25%=mild, 26-50%=moderate, 51-75%=good, 76-100%=excellent). RESULTS All participants completed the study. Of these, scores of nine patients were excellent, scores of five were good, and the score of one was moderate. Statistically significant percentage improvement of the clinical scores from baseline was seen at the end (p<.05).
Low-voltage RF treatment of XP is effective. If the lesions are too close to the eyes or are multiple or patched with indistinct borders, low-voltage RF can be used.
睑黄瘤（XP）是最常见的黄瘤形式，主要位于眼睑上。有多种治疗选择，但都存在一定的局限性，没有一种是令人满意的。
提供另一种治疗选择（低电压射频[RF]），并评估其在 XP 中的疗效。
本研究纳入了 15 名患者。患者在治疗前、治疗结束时和 5 个月后的随访时接受检查。通过比较治疗前后的照片，根据临床检查来判断改善情况。将双频 4.0-MHz RF 机器的电极应用于病变表面。使用 5 分制（0=无结果，0-25%=轻度，26-50%=中度，51-75%=良好，76-100%=优秀）计算临床评分。
所有参与者均完成了研究。其中，9 名患者的评分优秀，5 名患者的评分良好，1 名患者的评分中度。治疗结束时，临床评分的显著百分比改善具有统计学意义（p<.05）。
低电压 RF 治疗 XP 是有效的。如果病变太靠近眼睛，或者是多个或边界模糊的斑块，可使用低电压 RF。
