Pathania Vikas, Chatterjee Manas
Department of Dermatology, Military Hospital, Bareilly, Uttar Pradesh, India.
Department of Dermatology, Command Hospital, Kolkata, West Bengal, India.
J Cutan Aesthet Surg. 2015 Jan-Mar;8(1):46-9. doi: 10.4103/0974-2077.155084.
Xanthelasma palpebrarum is the most common form of xanthomas. Albeit a benign entity, it is cosmetically disturbing and a frequently recurring dermatologic referral. Although the classical treatment option remains surgical excision, alternatively, chemical cauterization, cryosurgery and electrofulguration have all been tried in the past with mixed results. The use of laser systems such as carbon dioxide laser, Erb:YAG laser, Q-switched Nd:YAG laser, diode laser, pulsed dye laser and KTP laser have become popular in the treatment of these lesions. Recent literature suggests minimal pigmentary changes and scarring with the use of ultrapulse carbon dioxide laser treatment of these lesions.
To study and evaluate the effectiveness of ultrapulse carbon dioxide laser ablation for treatment of xanthelasma palpebrarum.
10 patients presenting with bilateral xanthelasma palpebrarum, new and with recurrence were studied for results after a single treatment with ultrapulse carbon dioxide laser (10,600 nm; 100-200 Hz; 200-400 μsec). The follow-up time was 9 months.
All lesions were treatable with a single-laser treatment session. Two patients (20%) developed recurrence during the follow-up period. Side effects included post inflammatory hyperpigmentation in two patients (20%), but no visible scarring was observed.
The ultrapulse carbon dioxide laser is an effective and safe therapeutic alternative in treatment of xanthelasma palpebrarum.
睑黄瘤是最常见的黄瘤形式。尽管它是一种良性病变，但在美容方面令人困扰，且是皮肤科常见的复诊疾病。虽然经典的治疗方法仍是手术切除，但过去也曾尝试过化学烧灼、冷冻手术和电灼术，效果不一。诸如二氧化碳激光、铒：钇铝石榴石激光、调Q钕：钇铝石榴石激光、二极管激光、脉冲染料激光和倍频Nd:YAG激光等激光系统在治疗这些病变中已变得很流行。最近的文献表明，使用超脉冲二氧化碳激光治疗这些病变时色素沉着变化和瘢痕形成最少。
研究和评估超脉冲二氧化碳激光消融治疗睑黄瘤的有效性。
对10例双侧睑黄瘤患者（包括初发和复发患者）进行研究，采用超脉冲二氧化碳激光（波长10,600纳米；频率100 - 200赫兹；脉宽200 - 400微秒）单次治疗，随访时间为9个月。
所有病变均可通过单次激光治疗治愈。2例患者（20%）在随访期间复发。副作用包括2例患者（20%）出现炎症后色素沉着，但未观察到明显瘢痕形成。
超脉冲二氧化碳激光是治疗睑黄瘤的一种有效且安全的治疗选择。
