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心境障碍门诊患者持续性失业状况:频率及与人口统计学变量和共病障碍的相关性。

Sustained unemployment in psychiatric outpatients with bipolar disorder: frequency and association with demographic variables and comorbid disorders.

机构信息

Department of Psychiatry and Human Behavior, Brown Medical School, 135 Plain Street, Providence, RI 02905, USA.

出版信息

Bipolar Disord. 2010 Nov;12(7):720-6. doi: 10.1111/j.1399-5618.2010.00869.x.

Abstract

OBJECTIVES

The negative impact of bipolar disorder on occupational functioning is well established. However, few studies have examined the persistence of unemployment, and no studies have examined the association between diagnostic comorbidity and sustained unemployment. In the present report from the Rhode Island Methods to Improve Diagnostic Assessment and Services (MIDAS) project, we described the amount of time unemployed in the five years before the evaluation in a large cohort of outpatients diagnosed with bipolar disorder, and determined the demographic and clinical correlates of sustained unemployment.

METHODS

A total of 206 patients diagnosed with DSM-IV bipolar I or bipolar II disorder were interviewed with semi-structured interviews assessing comorbid Axis I and Axis II disorders, demographic and clinical variables. The interview included an assessment of the amount of time missed from work due to psychiatric reasons during the past five years. Persistent unemployment was defined as missing up to two years or more from work.

RESULTS

Less than 20% of the patients reported not missing any time from work due to psychiatric reasons, and more than one-third missed up to two years or more from work. Prolonged unemployment was associated with increased rates of current panic disorder and a lifetime history of alcohol abuse or dependence. Patients with prolonged unemployment were older and experienced more episodes of depression.

CONCLUSIONS

Most patients presenting for the treatment of bipolar disorder have missed some time from work due to psychiatric reasons, and the persistence of employment problems is considerable. Comorbid psychiatric disorders are a potentially treatable risk factor for sustained unemployment. It is therefore of public health significance to determine if current treatments are effective in bipolar disorder patients with current panic disorder, and if not, to attempt to develop treatments that are effective.

摘要

目的

双相情感障碍对职业功能的负面影响已得到充分证实。然而,很少有研究检查失业的持续性,也没有研究检查诊断共病与持续失业之间的关系。在罗德岛改善诊断评估和服务(MIDAS)项目的本报告中,我们描述了在接受双相情感障碍诊断的大样本门诊患者的评估前五年内失业的时间,并确定了持续失业的人口统计学和临床相关性。

方法

共有 206 名被诊断为 DSM-IV 双相 I 型或双相 II 型障碍的患者接受了半结构化访谈,评估了共病轴 I 和轴 II 障碍、人口统计学和临床变量。访谈包括评估过去五年因精神原因而错过工作的时间量。持续性失业定义为因工作缺勤长达两年或以上。

结果

不到 20%的患者报告因精神原因而没有错过任何工作时间,超过三分之一的患者缺勤长达两年或以上。长期失业与当前惊恐障碍和酒精滥用或依赖的终身病史相关。失业时间长的患者年龄较大,经历的抑郁发作次数更多。

结论

大多数因双相情感障碍接受治疗的患者因精神原因而错过了一些工作时间,并且就业问题的持续存在是相当大的。共病精神障碍是持续失业的一个潜在可治疗的风险因素。因此,确定当前的治疗方法在当前患有惊恐障碍的双相情感障碍患者中是否有效,并且如果没有,尝试开发有效的治疗方法,这对公共卫生具有重要意义。

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