Department of Nursing, Hung-Kuang University College of Medicine and Nursing, Sha Lu, Taiwan.
Pain Med. 2010 Dec;11(12):1849-58. doi: 10.1111/j.1526-4637.2010.00976.x. Epub 2010 Oct 28.
Clinicians and researchers have a very limited understanding of how acute pain after cardiac surgery may develop into chronic pain. The aims of this study were to describe the pattern of pain during the first 3 months after cardiac surgery and to examine the predictors of surgery-related chronic pain.
A prospective panel study was conducted to monitor changes in worst and average pain intensity before and during the first 3 months following cardiac surgery in a sample of Taiwanese patients. Fifty-three patients who underwent a midsternotomy rated pain intensity before surgery and at postoperative days 7, 10, 30, and 90. The participants also rated beliefs about opioid use, and their medical records were reviewed to document opioid use during the first week after surgery.
The patients who reported chronic pain 90 days following surgery showed an unusual pattern of an increase in pain from 10 to 30 days after surgery. Higher worst pain intensity ratings at 30 days following surgery and more negative beliefs in opioid use were both associated with a greater likelihood of reporting chronic pain at 3 months.
Patients reporting a pattern of increasing pain starting about 10 days after surgery and holding negative beliefs about opioid use are at risk of developing chronic pain and may require more careful monitoring and pain treatment. The possible benefits of interventions that minimize pain during the weeks after surgery and that alter negative beliefs about opioid use should be examined in future research.
临床医生和研究人员对心脏手术后急性疼痛如何发展为慢性疼痛知之甚少。本研究旨在描述心脏手术后前 3 个月的疼痛模式,并探讨与手术相关的慢性疼痛的预测因素。
本研究采用前瞻性队列研究,对接受正中切开术的台湾患者样本在心脏手术后前 3 个月内的最剧烈疼痛和平均疼痛强度的变化进行监测。53 名患者在术前以及术后第 7、10、30 和 90 天评估疼痛强度。参与者还评估了对阿片类药物使用的信念,并且回顾了他们的病历以记录术后第一周的阿片类药物使用情况。
术后 90 天报告慢性疼痛的患者表现出一种异常的疼痛模式,即在手术后 10 至 30 天内疼痛增加。术后 30 天最剧烈疼痛强度评分较高,以及对阿片类药物使用的更消极信念,均与报告术后 3 个月慢性疼痛的可能性更大相关。
报告从术后约 10 天开始疼痛增加且对阿片类药物使用持有消极信念的患者存在发生慢性疼痛的风险,可能需要更仔细的监测和疼痛治疗。未来的研究应探讨干预措施,这些措施可能会减轻手术后数周内的疼痛,并改变对阿片类药物使用的消极信念,从而带来可能的益处。