• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

使用葡萄糖酸氯己定进行术前清洁以降低手术部位感染风险的证据。

Evidence for using chlorhexidine gluconate preoperative cleansing to reduce the risk of surgical site infection.

作者信息

Edmiston Charles E, Okoli Obi, Graham Mary Beth, Sinski Sharon, Seabrook Gary R

机构信息

Department of Surgery, Medical College of Wisconsin, Milwaukee, USA.

出版信息

AORN J. 2010 Nov;92(5):509-18. doi: 10.1016/j.aorn.2010.01.020.

DOI:10.1016/j.aorn.2010.01.020
PMID:21040815
Abstract

Surgical site infections are associated with significant patient morbidity and mortality and are the third most frequently reported health care-associated infection. A suggested risk reduction strategy has been the preadmission shower or skin cleansing with chlorhexidine gluconate (CHG). Although older clinical trials question the clinical efficacy of cleansing with CHG, recent evidence-based scientific and clinical studies support two types of CHG application (ie, a 2% CHG-coated cloth or 4% CHG soap) using a standardized, timed process before hospital admission as an effective strategy for reducing the risk of postoperative surgical site infection.

摘要

手术部位感染与患者的高发病率和死亡率相关,是报告频率第三高的医疗保健相关感染。一种建议的降低风险策略是入院前淋浴或用葡萄糖酸氯己定(CHG)进行皮肤清洁。尽管早期临床试验对使用CHG清洁的临床疗效提出质疑,但最近基于证据的科学和临床研究支持在入院前使用标准化的定时流程应用两种类型的CHG(即2%的CHG涂层布或4%的CHG肥皂),作为降低术后手术部位感染风险的有效策略。

相似文献

1
Evidence for using chlorhexidine gluconate preoperative cleansing to reduce the risk of surgical site infection.使用葡萄糖酸氯己定进行术前清洁以降低手术部位感染风险的证据。
AORN J. 2010 Nov;92(5):509-18. doi: 10.1016/j.aorn.2010.01.020.
2
Reducing the risk of surgical site infections: does chlorhexidine gluconate provide a risk reduction benefit?降低手术部位感染风险:葡萄糖酸洗必泰是否具有降低风险的益处?
Am J Infect Control. 2013 May;41(5 Suppl):S49-55. doi: 10.1016/j.ajic.2012.10.030.
3
Preoperative shower revisited: can high topical antiseptic levels be achieved on the skin surface before surgical admission?再次探讨术前沐浴:手术入院前皮肤表面能否达到高浓度局部抗菌水平?
J Am Coll Surg. 2008 Aug;207(2):233-9. doi: 10.1016/j.jamcollsurg.2007.12.054. Epub 2008 May 23.
4
Preadmission Application of 2% Chlorhexidine Gluconate (CHG): Enhancing Patient Compliance While Maximizing Skin Surface Concentrations.2%葡萄糖酸氯己定(CHG)的入院前应用:提高患者依从性并使皮肤表面浓度最大化
Infect Control Hosp Epidemiol. 2016 Mar;37(3):254-9. doi: 10.1017/ice.2015.303. Epub 2015 Dec 28.
5
Effectiveness of 2% CHG cloth bathing for reducing surgical site infections.2%洗必泰布浴预防手术部位感染的有效性
AORN J. 2013 May;97(5):547-51. doi: 10.1016/j.aorn.2013.02.009.
6
Evidence for a Standardized Preadmission Showering Regimen to Achieve Maximal Antiseptic Skin Surface Concentrations of Chlorhexidine Gluconate, 4%, in Surgical Patients.术前沐浴标准化方案以实现手术患者葡萄糖酸洗必泰 4%的最大皮肤表面抗菌浓度的证据。
JAMA Surg. 2015 Nov;150(11):1027-33. doi: 10.1001/jamasurg.2015.2210.
7
Presurgical skin preparation with a novel 2% chlorhexidine gluconate cloth reduces rates of surgical site infection in orthopaedic surgical patients.使用新型2%葡萄糖酸氯己定布进行术前皮肤准备可降低骨科手术患者手术部位感染率。
Orthop Nurs. 2009 May-Jun;28(3):141-5. doi: 10.1097/NOR.0b013e3181a469db.
8
Comparative of a new and innovative 2% chlorhexidine gluconate-impregnated cloth with 4% chlorhexidine gluconate as topical antiseptic for preparation of the skin prior to surgery.新型创新型2%葡萄糖酸氯己定浸渍布与4%葡萄糖酸氯己定作为术前皮肤准备局部防腐剂的比较。
Am J Infect Control. 2007 Mar;35(2):89-96. doi: 10.1016/j.ajic.2006.06.012.
9
Does Preadmission Cutaneous Chlorhexidine Preparation Reduce Surgical Site Infections After Total Knee Arthroplasty?术前皮肤氯己定准备能否降低全膝关节置换术后手术部位感染的发生率?
Clin Orthop Relat Res. 2016 Jul;474(7):1592-8. doi: 10.1007/s11999-016-4767-6.
10
Does Preadmission Cutaneous Chlorhexidine Preparation Reduce Surgical Site Infections After Total Hip Arthroplasty?术前皮肤氯己定准备能否降低全髋关节置换术后手术部位感染?
Clin Orthop Relat Res. 2016 Jul;474(7):1583-8. doi: 10.1007/s11999-016-4748-9.

引用本文的文献

1
Design of a Dual-Drug Delivery System for Local Release of Chlorhexidine and Dexketoprofen.用于氯己定和右酮洛芬局部释放的双药递送系统的设计
Polymers (Basel). 2025 Jun 26;17(13):1771. doi: 10.3390/polym17131771.
2
[Recommendations for perioperative skin care in total joint arthroplasty: antimicrobial wash lotion, precleaning and hair removal].全关节置换术中围手术期皮肤护理的建议:抗菌洗液、术前清洁和毛发去除
Orthopadie (Heidelb). 2025 Feb;54(2):102-107. doi: 10.1007/s00132-024-04605-4. Epub 2025 Jan 31.
3
Synthesis, Drug Release, and Antibacterial Properties of Novel Dendritic CHX-SrCl and CHX-ZnCl Particles.
新型树枝状CHX-SrCl和CHX-ZnCl颗粒的合成、药物释放及抗菌性能
Pharmaceutics. 2021 Oct 27;13(11):1799. doi: 10.3390/pharmaceutics13111799.
4
"Recommendations for periprosthetic joint infections (PJI) prevention: the European Knee Associates (EKA)-International Committee American Association of Hip and Knee Surgeons (AAHKS)-Arthroplasty Society in Asia (ASIA) survey of members".“人工关节周围感染(PJI)预防建议:欧洲膝关节协会(EKA)-美国髋关节和膝关节外科医师协会(AAHKS)-亚洲关节置换学会(ASIA)对成员的调查”。
Knee Surg Sports Traumatol Arthrosc. 2022 Dec;30(12):3932-3943. doi: 10.1007/s00167-021-06742-1. Epub 2021 Sep 13.
5
Are preoperative chlorhexidine gluconate showers associated with a reduction in surgical site infection following craniotomy? A retrospective cohort analysis of 3126 surgical procedures.术前使用葡萄糖酸氯己定沐浴是否与开颅术后手术部位感染的减少有关?对3126例外科手术的回顾性队列分析。
J Neurosurg. 2021 Apr 30;135(6):1889-1897. doi: 10.3171/2020.10.JNS201255. Print 2021 Dec 1.
6
Progress in Prevention, Diagnosis, and Treatment of Periprosthetic Joint Infection.人工关节周围感染的预防、诊断与治疗进展
Evid Based Complement Alternat Med. 2021 Jan 20;2021:3023047. doi: 10.1155/2021/3023047. eCollection 2021.
7
Society for Vascular Nursing endovascular repair of abdominal aortic aneurysm updated nursing clinical practice guideline.血管护理学会腹主动脉瘤血管内修复术更新的护理临床实践指南。
J Vasc Nurs. 2020 Jun;38(2):36-65. doi: 10.1016/j.jvn.2020.01.004. Epub 2020 May 21.
8
Preoperative Antisepsis with Chlorhexidine Versus Povidone-Iodine for the Prevention of Surgical Site Infection: a Systematic Review and Meta-analysis.术前氯己定与聚维酮碘消毒预防手术部位感染的比较:系统评价和荟萃分析。
World J Surg. 2020 May;44(5):1412-1424. doi: 10.1007/s00268-020-05384-7.
9
Should preoperative showering or cleansing with chlorhexidine gluconate (CHG) be part of the surgical care bundle to prevent surgical site infection?术前使用葡萄糖酸氯己定(CHG)沐浴或清洁是否应作为手术护理包的一部分以预防手术部位感染?
J Infect Prev. 2017 Nov;18(6):311-314. doi: 10.1177/1757177417714873. Epub 2017 Jul 26.
10
Does Preadmission Cutaneous Chlorhexidine Preparation Reduce Surgical Site Infections After Total Knee Arthroplasty?术前皮肤氯己定准备能否降低全膝关节置换术后手术部位感染的发生率?
Clin Orthop Relat Res. 2016 Jul;474(7):1592-8. doi: 10.1007/s11999-016-4767-6.