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舌下间隙施万细胞瘤:一种位于独特解剖位置的罕见肿瘤。

Sublingual Space Schwannoma: An Uncommon Tumour in a Unique Anatomical Location.

作者信息

Davidson B I R, Nayani Divya, Nampally Vamshi Krishna, Pitale Ashok Rahul Kumar

机构信息

Department of Otorhinolaryngology, Osmania Medical College, Government ENT Hospital, Door No 5-1-174, Opposite State Bank of India Head Office, Bank Street Road, Koti, Hyderabad, 500095 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Jun;76(3):2906-2909. doi: 10.1007/s12070-024-04558-2. Epub 2024 Mar 9.

Abstract

A Schwannoma is a benign tumour originating from Schwann cells within the peripheral, cranial, or autonomic nerves. Typically, these tumours manifest as a solitary, slow-growing mass with smooth surface, usually devoid of significant symptoms. Schwannomas most frequently appear in individuals aged 30-50 years. Although they are relatively uncommon, approximately one-fourth of all Schwannomas are found in the head and neck area. Its occurrence within the oral cavity, with the tongue being the most common site, followed by the palate, floor of the mouth, buccal mucosa, lips, and jaws. Diagnosing these tumours before surgery can be challenging, and in most instances, a definitive diagnosis can only be established through surgical intervention and subsequent histological examination. Immunohistochemistry plays a crucial role in confirming the diagnosis, as it shows that Schwannoma cells exhibit a positive reaction to the S-100 protein. Here, we present a case of a Schwannoma in the floor of the mouth, observed in an 18-year-old male patient.

摘要

施万细胞瘤是一种起源于周围神经、颅神经或自主神经中施万细胞的良性肿瘤。通常,这些肿瘤表现为单个、生长缓慢、表面光滑的肿块,通常没有明显症状。施万细胞瘤最常出现在30至50岁的人群中。虽然它们相对不常见,但所有施万细胞瘤中约四分之一发生在头颈部区域。其在口腔内的发生部位,最常见于舌部,其次是腭部、口底、颊黏膜、唇部和颌骨。在手术前诊断这些肿瘤具有挑战性,在大多数情况下,只有通过手术干预及随后的组织学检查才能确立明确诊断。免疫组织化学在确诊中起着关键作用,因为它显示施万细胞瘤细胞对S-100蛋白呈阳性反应。在此,我们报告一例发生于口底的施万细胞瘤,该病例见于一名18岁男性患者。

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