Ilgen Mark A, Bohnert Amy S B, Ignacio Rosalinda V, McCarthy John F, Valenstein Marcia M, Kim H Myra, Blow Frederic C
Veterans Affairs Serious Mental Illness Treatment Research and Evaluation Center, Department of Veterans Affairs Healthcare System, University of Michigan, Ann Arbor, MI, USA.
Arch Gen Psychiatry. 2010 Nov;67(11):1152-8. doi: 10.1001/archgenpsychiatry.2010.129.
Although numerous studies have documented the clear link between psychiatric conditions and suicide, few have allowed for the comparison between the strength of association between different psychiatric diagnoses and suicide.
To examine the strength of association between different types of psychiatric diagnoses and the risk of suicide in patients receiving health care services from the Department of Veterans Affairs in fiscal year (FY) 1999.
This project examined National Death Index data and Veterans Health Administration patient treatment records.
Department of Veterans Affairs, Veterans Health Administration.
All veterans who used Veterans Health Administration services during FY 1999 (N = 3 291 891) who were alive at the start of FY 2000.
Psychiatric diagnoses were obtained from patient treatment records in FY 1998 and 1999 and used to predict subsequent death by suicide during the following 7 years in sex-stratified survival analyses controlling for age.
In the 7 years after FY 1999, 7684 veterans died by suicide. In diagnosis-specific analyses, patients with bipolar disorder had the greatest estimated risk of suicide among men (hazard ratio, 2.98; 95% confidence interval, 2.73-3.25), and patients with substance use disorders had the greatest risk among women (6.62; 4.72-9.29).
Although all the examined psychiatric diagnoses were associated with elevated risk of suicide in veterans, results indicate that men with bipolar disorder and women with substance use disorders are at particularly elevated risk for suicide.
尽管众多研究已证明精神疾病与自杀之间存在明确关联,但很少有研究对不同精神疾病诊断与自杀之间关联的强度进行比较。
研究1999财年接受退伍军人事务部医疗服务的患者中,不同类型精神疾病诊断与自杀风险之间关联的强度。
本项目研究了国家死亡指数数据和退伍军人健康管理局患者治疗记录。
退伍军人事务部,退伍军人健康管理局。
所有在1999财年使用退伍军人健康管理局服务且在2000财年开始时仍在世的退伍军人(N = 3291891)。
从1998年和1999年的患者治疗记录中获取精神疾病诊断信息,并在按性别分层的生存分析中用于预测随后7年内因自杀导致的死亡,分析时控制了年龄因素。
在1999财年后的7年里,7684名退伍军人自杀身亡。在特定诊断分析中,双相情感障碍患者在男性中自杀风险估计最高(风险比,2.98;95%置信区间,2.73 - 3.25),物质使用障碍患者在女性中自杀风险最高(6.62;4.72 - 9.29)。
尽管所有研究的精神疾病诊断都与退伍军人自杀风险升高有关,但结果表明,患有双相情感障碍的男性和患有物质使用障碍的女性自杀风险尤其高。