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[Reflotron便携式分析仪在基层医疗中测定胆固醇的评估]

[An evaluation of the Reflotron portable analyzer for cholesterol determination in primary care].

作者信息

Torres Garrido M, Aragonès Benaiges E, Sarrà Manetas N, Vives Ballester J A, Gutiérrez Mendoza I, Borràs Martínez P, Gómez Sorribes A

机构信息

CAP La Granja-Torreforta, Tarragona.

出版信息

Aten Primaria. 1990 May;7 Spec No:34-7.

PMID:2104170
Abstract

We have evaluated serum cholesterol in a primary care center with a recently introduced portable analyzer: Reflotron (Boehringer Mannheim). The linearity and exactitude were investigated with Hitachi 704 (Boehringer Mannheim) used in the reference laboratory. Accuracy was also tested. We found a good accuracy after repeated analysis (n = 30) of two control sera with a variation coefficient of 2.77% in the first (mean = 125.14 mg/dl, SD 3.47) and 2.94% (mean = 254.53 mg/dl, SD 7.49) in the second. We found an overall lack of accuracy of Reflotron with a more pronounced negative bias in capillary blood (mean d = 30.93 mg/dl, dSE 3.25) than in serum (mean d = dSE 1.12). We found a positive linear correlation both using serum (r = 0.9845; n = 45) and capillary blood (r = 0.9094; n = 30). We feel that Reflotron is useful for primary care due to its good accuracy and linearity regarding the reference method, but its inexactitud should be taken into account. We emphasize the need for quality control to investigate its limitations when the results are analyzed.

摘要

我们在一家基层医疗中心使用最近引进的便携式分析仪Reflotron(勃林格殷格翰公司)评估了血清胆固醇水平。用参考实验室使用的日立704(勃林格殷格翰公司)分析仪研究了其线性和准确性。还对准确性进行了测试。我们对两份对照血清进行了30次重复分析后发现准确性良好,第一份血清的变异系数为2.77%(均值 = 125.14mg/dl,标准差3.47),第二份血清的变异系数为2.94%(均值 = 254.53mg/dl,标准差7.49)。我们发现Reflotron总体准确性欠佳,与血清相比,毛细血管血中的负偏差更明显(平均差值d = 30.93mg/dl,标准误3.25)(血清中平均差值d = 标准误1.12)。无论是使用血清(r = 0.9845;n = 45)还是毛细血管血(r = 0.9094;n = 30),我们都发现了正线性相关性。我们认为,Reflotron因其相对于参考方法具有良好的准确性和线性,对基层医疗有用,但应考虑到其不精确性。我们强调在分析结果时需要进行质量控制以研究其局限性。

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