Suppr超能文献

奥克兰卒中结局研究。第 1 部分:性别、卒中类型、种族和卒中后 5 年的功能结局。

Auckland Stroke Outcomes Study. Part 1: Gender, stroke types, ethnicity, and functional outcomes 5 years poststroke.

机构信息

National Institute for Stroke and Applied Neurosciences, School of Rehabilitation and Occupation Studies, Faculty of Health and Environmental Studies, AUT University, AUT North Shore Campus, 90 Akoranga Dr., Auckland 1142, New Zealand.

出版信息

Neurology. 2010 Nov 2;75(18):1597-607. doi: 10.1212/WNL.0b013e3181fb44b3.

Abstract

BACKGROUND

Studying long-term stroke outcomes including body functioning (neurologic and neuropsychological impairments) and activity limitations and participation is essential for long-term evidence-based rehabilitation and service planning, resource allocation, and improving health outcomes in stroke. However, reliable data to address these issues is lacking.

METHODS

This study (February 2007-December 2008) sourced its participants from the population-based incidence study conducted in Auckland in 2002-2003. Participants completed structured self-administered questionnaires, and a face-to-face interview including a battery of neuropsychological tests. Logistic regression analysis was used to analyze associations between and within functional outcomes and their potential predictors.

RESULTS

Of 418 5-year stroke survivors, two-thirds had good functional outcome in terms of neurologic impairment and disability (defined as modified Rankin Score <3), 22.5% had cognitive impairment indicative of dementia, 20% had experienced a recurrent stroke, almost 15% were institutionalized, and 29.6% had symptoms suggesting depression. Highly significant correlations were found between and within various measurements of body functioning (especially neuropsychological impairments), activity, and participation. Age, dependency, and depression were independently associated with most outcomes analyzed.

CONCLUSIONS

The strong associations between neuropsychological impairment and other functional outcomes and across various measurements of body functioning, activity, and participation justify utilizing a multidisciplinary approach to studying and managing long-term stroke outcomes. Observed gender and ethnic differences in some important stroke outcomes warrant further investigations.

摘要

背景

研究长期的中风预后,包括身体功能(神经和神经心理学损伤)和活动受限及参与度,对于长期循证康复和服务规划、资源分配以及改善中风患者的健康结果至关重要。然而,缺乏可靠的数据来解决这些问题。

方法

本研究(2007 年 2 月至 2008 年 12 月)的参与者来自于 2002 年至 2003 年在奥克兰进行的基于人群的发病研究。参与者完成了结构化的自我管理问卷,以及包括一系列神经心理学测试的面对面访谈。逻辑回归分析用于分析功能预后及其潜在预测因素之间和内部的关联。

结果

在 418 名 5 年中风幸存者中,三分之二的人在神经损伤和残疾方面(定义为改良 Rankin 评分<3)有良好的功能预后,22.5%的人有认知障碍,提示痴呆,20%的人经历过再次中风,近 15%的人被收容,29.6%的人有抑郁症状。身体功能(尤其是神经心理学损伤)、活动和参与的各种测量之间存在显著的相关性。年龄、依赖性和抑郁与大多数分析的结果独立相关。

结论

神经心理学损伤与其他功能预后之间以及身体功能、活动和参与的各种测量之间存在很强的关联,这证明了采用多学科方法来研究和管理长期中风预后是合理的。在一些重要的中风预后方面观察到的性别和种族差异需要进一步研究。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验