Adlam David, Cuculi Florim, Lim Chris, Banning Adrian
Oxford Heart Centre, John Radcliffe Hospital, OX3 9DU, Oxford, United Kingdom.
J Invasive Cardiol. 2010 Nov;22(11):549-53.
Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndromes. The increasing use of early angiography in the primary percutaneous coronary intervention (PPCI) era has led to earlier identification of patients with SCAD and may encourage an increased use of percutaneous revascularization strategies in this population. However, the pathophysiology of SCAD is distinct from the usually stenotic atherosclerotic plaque-rupture events responsible for most ST-elevation and non-ST-elevation myocardial infarctions, but our approach to managing these patients utilizes largely the same medical and revascularization therapies used in conventional acute coronary syndromes. This review examines the literature on SCAD and contemporary management issues.
自发性冠状动脉夹层(SCAD)是急性冠状动脉综合征的一种罕见病因。在直接经皮冠状动脉介入治疗(PPCI)时代,早期血管造影术的使用日益增加,这使得SCAD患者能够被更早地识别出来,并且可能促使针对这一人群更多地采用经皮血管重建策略。然而,SCAD的病理生理学与导致大多数ST段抬高型和非ST段抬高型心肌梗死的通常狭窄的动脉粥样硬化斑块破裂事件不同,但是我们对这些患者的管理方法在很大程度上采用了与传统急性冠状动脉综合征相同的药物和血管重建治疗方法。本综述探讨了有关SCAD及当代管理问题的文献。