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真性红细胞增多症合并内脏静脉血栓形成患者出现伴有肺栓塞的移动性右心血栓。

Mobile right heart thrombus with pulmonary embolism in a patient with polycythemia rubra vera and splanchnic vein thrombosis.

作者信息

Panduranga Prashanth, Mukhaini Mohammed, Saleem Muhammad, Al-Delamie Taha, Zachariah Sunny, Al-Taie Saqar

机构信息

Department of Cardiology, Royal Hospital, Muscat, Oman.

出版信息

Heart Views. 2010 Mar;11(1):16-20.

PMID:21042459
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2964707/
Abstract

Splanchnic vein thrombosis in patients with polycythemia rubra vera is well-known. Development of mobile right heart thrombus in these patients has not been reported previously. We describe a young patient with Polycythemia rubra vera and splanchnic vein thrombosis with ischemic bowel who underwent small bowel resection. He developed a large mobile right atrial thrombus and bilateral pulmonary embolism. He also had upper gastrointestinal bleed. His management was complicated and challenging due to multiple risk factors and co-morbid conditions. Thrombolysis was contraindicated and he refused surgical intervention. He was treated with anticoagulation with complete resolution of right atrial thrombus.

摘要

真性红细胞增多症患者发生内脏静脉血栓形成是众所周知的。此前尚未有这些患者发生可移动性右心血栓的报道。我们描述了一名患有真性红细胞增多症和内脏静脉血栓形成并伴有缺血性肠病的年轻患者,该患者接受了小肠切除术。他出现了一个巨大的可移动性右心房血栓和双侧肺栓塞。他还发生了上消化道出血。由于多种危险因素和合并症,他的治疗复杂且具有挑战性。溶栓治疗存在禁忌,且他拒绝手术干预。他接受了抗凝治疗,右心房血栓完全溶解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5af/2964707/27213ae3503f/HV-11-16-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5af/2964707/36ff91949063/HV-11-16-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5af/2964707/0f0cf8c72a9d/HV-11-16-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5af/2964707/0016032623e4/HV-11-16-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5af/2964707/2425427fe986/HV-11-16-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5af/2964707/4811d8a17c7a/HV-11-16-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5af/2964707/27213ae3503f/HV-11-16-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5af/2964707/36ff91949063/HV-11-16-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5af/2964707/0f0cf8c72a9d/HV-11-16-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5af/2964707/0016032623e4/HV-11-16-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5af/2964707/2425427fe986/HV-11-16-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5af/2964707/4811d8a17c7a/HV-11-16-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5af/2964707/27213ae3503f/HV-11-16-g006.jpg

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Free-floating right atrial thrombus with acute pulmonary embolism.
Thorax. 2009 Aug;64(8):736. doi: 10.1136/thx.2008.108217.
2
Contrast-enhanced right atrial mass: tumour or thrombus?增强扫描显示右心房肿块:肿瘤还是血栓?
Eur J Echocardiogr. 2009 Mar;10(2):365-6. doi: 10.1093/ejechocard/jen310. Epub 2008 Dec 9.
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A new JAK2 gene mutation in patients with polycythemia vera and splanchnic vein thrombosis.真性红细胞增多症和内脏静脉血栓形成患者中的一种新的JAK2基因突变。
Blood. 2007 Oct 1;110(7):2768-9. doi: 10.1182/blood-2007-05-092502.
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Value of transthoracic echocardiography in therapy regimens evaluation in pulmonary embolism.经胸超声心动图在肺栓塞治疗方案评估中的价值
J Thromb Thrombolysis. 2008 Dec;26(3):251-6. doi: 10.1007/s11239-007-0087-8. Epub 2007 Aug 21.
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When should we thrombolyse patients with pulmonary embolism? A systematic review of the literature.我们应该在何时对肺栓塞患者进行溶栓治疗?一项文献系统综述。
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Mobile thrombi of the right heart in pulmonary embolism: delayed disappearance after thrombolytic treatment.肺栓塞中右心的移动性血栓:溶栓治疗后延迟消失
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Prevalence and risk of pulmonary embolism in patients with intracardiac thrombosis: a population-based study of 23 796 consecutive autopsies.心内血栓形成患者肺栓塞的患病率及风险:一项基于23796例连续尸检的人群研究。
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