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[终丝室管膜瘤。20例连续病例分析]

[Filum terminale ependymomas. Analysis of a serie of 20 consecutive cases].

作者信息

Gelabert-González M, Arcos-Algaba A, Serramito-García R, Castro-Bouzas D, Santín-Amo J M, Aran-Echabe E, Prieto-González A, Bandin-Diéguez F J, García-Allut A

机构信息

Servicio de Neurocirugía, Hospital Clínico Universitario de Santiago de Compostela, Departamento de Cirugía, Universidad de Santiago de Compostela.

出版信息

Neurocirugia (Astur). 2010 Oct;21(5):381-9.

PMID:21042689
Abstract

OBJECTIVE

to analyze the clinical, radiological and surgical outcome of a series of filum terminale ependymomas. Patients and methods. This retrospective study involved 20 patients with 21 ependymomas of the filum terminale encountered during a 21 year period (1988- 2008). All patients were diagnosed using MRI and surgically treated.

RESULTS

the male: female ratio was 1:1.5, and the mean age at diagnosis was 44.8 years (range 15-64). First symptom included radicular pain (12 cases) and lumbar pain in the other 8 cases, with average symptom duration of 8.7 years (range 0-6-32). All patients underwent open biopsy, seventeen tumours received gross-total resection and 4 received subtotal resection. Histologically, 20 tumours were myxopapillary ependymomas (grade I) and 1 case a grade II ependymoma. The mean follow-up period was 8 years (range 1-18 years).

CONCLUSIONS

filum terminale ependimomas are slow growing tumours of the cauda equina with a high incidence in young adults. The most common presentation is with low back pain long time evolution. Although ependymomas of the filum terminale are thought to be benign, local recurrence is not uncommon.

摘要

目的

分析一系列终丝室管膜瘤的临床、影像学及手术结果。患者与方法。本回顾性研究纳入了21年间(1988 - 2008年)遇到的20例患者的21例终丝室管膜瘤。所有患者均通过磁共振成像(MRI)诊断并接受手术治疗。

结果

男女比例为1:1.5,诊断时的平均年龄为44.8岁(范围15 - 64岁)。首发症状包括神经根性疼痛(12例),其他8例为腰痛,平均症状持续时间为8.7年(范围0.6 - 32年)。所有患者均接受了开放性活检,17例肿瘤实现了全切,4例为次全切除。组织学上,20例肿瘤为黏液乳头型室管膜瘤(I级),1例为II级室管膜瘤。平均随访期为8年(范围1 - 18年)。

结论

终丝室管膜瘤是马尾神经生长缓慢的肿瘤,在年轻人中发病率较高。最常见的表现是长期的腰痛。尽管终丝室管膜瘤被认为是良性的,但局部复发并不少见。

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[Filum terminale ependymomas. Analysis of a serie of 20 consecutive cases].[终丝室管膜瘤。20例连续病例分析]
Neurocirugia (Astur). 2010 Oct;21(5):381-9.
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Paraganglioma of the cauda equina.马尾神经节细胞瘤
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Surgery for primary filum terminale ependymomas: outcome and prognostic factors.原发性终丝室管膜瘤的手术治疗:结果与预后因素
CNS Neurosci Ther. 2014 Feb;20(2):131-9. doi: 10.1111/cns.12174. Epub 2013 Nov 27.
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Acute neurological deterioration as a result of two synchronous hemorrhagic spinal ependymomas.由于两个同步出血性脊髓室管膜瘤导致的急性神经功能恶化。
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