Celli P, Cervoni L, Cantore G
Department of Neurological Sciences, Neurosurgery, La Sapienza University of Rome, Italy.
Acta Neurochir (Wien). 1993;124(2-4):99-103. doi: 10.1007/BF01401130.
A series of 28 ependymomas arising in the filum terminale was divided into two groups based on the presence/absence of connections with the conus medullaris and/or roots of the cauda equina. Group A comprised ependymomas having no connections with the contiguous structures and group B those either infiltrating or adhering to such structures. Factors having a positive influence on the prognosis (risk of recurrence) were: 1) clinical history under one year (p < 0.01); 2) confinement of tumour to the filum terminale (p < 0.01); 3) total tumour removal (p < 0.05). Postoperative radiotherapy had no appreciable effect on outcome. The combination of significant factors was in turn significantly influenced by the mode of tumour growth, which proved to be the cardinal factor in prognosis. This point is examined in the light of the published work.
一组28例发生于终丝的室管膜瘤根据其与脊髓圆锥和/或马尾神经根有无连接分为两组。A组包括与相邻结构无连接的室管膜瘤，B组包括浸润或附着于这些结构的室管膜瘤。对预后（复发风险）有积极影响的因素为：1）临床病史少于1年（p<0.01）；2）肿瘤局限于终丝（p<0.01）；3）肿瘤全切（p<0.05）。术后放疗对预后无明显影响。重要因素的组合又受到肿瘤生长方式的显著影响，而肿瘤生长方式被证明是预后的关键因素。根据已发表的研究对此点进行了探讨。
