Nirmala C, Nagarajappa A H
Department of Pathology, Bangalore Medical College & Research Institute, Bangalore.
Indian J Tuberc. 2010 Jul;57(3):160-4.
We report a case of erythema induratum recently encountered in our centre. A 14-year-old male presented with history of fever, weight loss and multiple, painful, hyperpigmented patches over both legs and dorsum of foot, since six months. FNAC showed evidence of granulomatous inflammation. Biopsy of the lesion showed skin with inflammatory infiltrate in the deep dermis composed predominantly of epithelioid granulomas, Langhan's giant cells and mature lymphocytes. A strongly positive Mantoux test and elevated TB IgG and IgM antibody levels suggested tuberculosis. The patient responded well to a course of anti-tuberculous therapy with marked resolution of the lesions.
我们报告了近期在我们中心遇到的一例硬结性红斑病例。一名14岁男性，自六个月以来，有发热、体重减轻的病史，双腿及足背部出现多个疼痛性色素沉着斑。细针穿刺抽吸活检显示有肉芽肿性炎症的证据。病变组织活检显示，真皮深层有炎症浸润，主要由上皮样肉芽肿、朗汉斯巨细胞和成熟淋巴细胞组成。结核菌素试验强阳性以及结核IgG和IgM抗体水平升高提示为结核病。该患者对抗结核治疗疗程反应良好，病变明显消退。
