Yazici Mesut, Ozkisacik Sezen, Oztan M Onur, Gürsoy Harun
Department of Pediatric Surgery, Adnan Menderes University Faculty of Medicine, Aydmn, Turkey.
Turk J Pediatr. 2010 Jul-Aug;52(4):400-3.
Total leukocyte count (TLC) and neutrophil count are not reliable parameters in the diagnosis of appendicitis in children, necessitating a search for more sensitive criteria. This study's goal was to investigate the diagnostic value of neutrophil/lymphocyte (N/L) ratio in childhood appendicitis. The patients admitted for acute abdominal symptoms were reviewed retrospectively. Data collected included initial preoperative TLC, together with neutrophil and lymphocyte values. N/L ratio was calculated by dividing the values obtained. One hundred eighty-three of 240 patients were treated operatively and were proven as appendicitis histopathologically. The other observed 57 cases were accepted as non-specific abdominal pain (NAP). 90.2% of the appendicitis group and 12.3% of the NAP group had N/L ratio higher than 3.5. The results indicate that N/L ratio seems to be a more sensitive parameter than TLC when evaluated retrospectively. N/L ratio of 3.5 can be used in the prediction of appendicitis in children.
白细胞总数（TLC）和中性粒细胞计数在儿童阑尾炎诊断中并非可靠参数，因此需要寻找更敏感的标准。本研究的目的是探讨中性粒细胞/淋巴细胞（N/L）比值在儿童阑尾炎中的诊断价值。对因急性腹部症状入院的患者进行回顾性分析。收集的数据包括术前初始TLC以及中性粒细胞和淋巴细胞值。通过将所得值相除计算N/L比值。240例患者中有183例接受了手术治疗，经组织病理学证实为阑尾炎。其余观察到的57例被诊断为非特异性腹痛（NAP）。阑尾炎组中90.2%以及NAP组中12.3%的患者N/L比值高于3.5。结果表明，回顾性评估时，N/L比值似乎是比TLC更敏感的参数。N/L比值为3.5可用于预测儿童阑尾炎。
