Sol Sherry Thrombosis Research Center, 3400 North Broad Street, Philadelphia, PA, 19140, USA, (215) 707-4684, (215) 707-2783.
Platelets. 1995;6(2):61-70. doi: 10.3109/09537109509078445.
Platelets respond to a wide variety of exogenous agonists that bind to distinct receptors on the platelet surface resulting in the intracellular generation of second messengers or the opening of ion channels, setting off a cascade of events leading to both physical and functional changes in the platelet. The cyclic nucleotides, cyclic adenosine 3'5'-monophosphate (CAMP) and cyclic guanosine 3'5'-monophosphate (cGMP) initiate a sequence of intracellular events that modulate many of these reactions in the platelet.
血小板对各种外源激动剂作出反应，这些激动剂与血小板表面的特定受体结合，导致细胞内第二信使的产生或离子通道的开放，引发一连串事件，导致血小板的物理和功能变化。环核苷酸，环腺苷酸 3'5'-单磷酸 (CAMP) 和环鸟苷酸 3'5'-单磷酸 (cGMP) 启动一系列细胞内事件，调节血小板中的许多这些反应。
