Department of Periodontics, S.M.B.T. Dental College and Hospital, Sangamner, Maharashtra, India.
J Periodontol. 2011 Apr;82(4):652-5. doi: 10.1902/jop.2010.100494. Epub 2010 Nov 2.
This paper is the first-ever report, to our knowledge, of a case of generalized primary gingival pseudoepitheliomatous hyperplasia(PEH) with significant periodontal findings in a 23-year-old Indian female patient. It explains the need to differentiate PEH from squamous cell carcinoma in diagnosis and treatment planning. The present article also reviews current immunohistologic staining methods used to differentiate PEH from squamous cell carcinoma.
A two-stage surgical approach was used to eliminate the lesion by gingivectomy and gingivoplasty under local anesthesia. Histopathologic examination of excised tissue was done to differentiate it from squamous cell carcinoma.
After 1-year follow-up, there was uneventful gingival healing and no recurrence of the lesion.
Differentiation of PEH from squamous cell carcinoma of the gingiva is important for diagnosis and treatment. It is also important to consider PEH as a rare condition of gingival overgrowth.
据我们所知，这是首例报告，一位 23 岁的印度女性患者出现了广泛的原发性牙龈假上皮瘤性增生（PEH）和显著的牙周表现。它解释了在诊断和治疗计划中需要将 PEH 与鳞状细胞癌区分开来的必要性。本文还回顾了目前用于区分 PEH 与鳞状细胞癌的免疫组织化学染色方法。
采用两阶段手术方法，在局部麻醉下通过牙龈切除术和牙龈成形术消除病变。对切除组织进行组织病理学检查，以将其与鳞状细胞癌区分开来。
1 年随访后，牙龈愈合顺利，无病变复发。
将 PEH 与牙龈鳞状细胞癌区分开来对诊断和治疗很重要。同样重要的是要将 PEH 视为一种罕见的牙龈过度生长情况。
