Iida K, Sugishita Y, Yukisada K, Ito I
Department of Internal Medicine, University of Tsukuba.
J Cardiol. 1990;20(2):301-10.
The clinical features of 20 patients with mildly dilated cardiomyopathy (MDCM) were investigated by electrocardiography and echocardiography. MDCM was defined as conditions with: 1) left ventricular end-diastolic dimension between 55 and 65 mm and 2) left ventricular fractional shortening between 10 and 25%. Nine patients (45%) had no histories of congestive heart failure. Eight patients had atrial fibrillation, and the other 12 patients were in regular sinus rhythm. Two patients had supraventricular premature contractions and five patients had ventricular premature contractions. One patient had paroxysmal atrial tachycardia. During the 40-months' span of this echocardiographic study, left ventricular end-diastolic dimension (60.8 +/- 3.8 mm to 57.3 +/- 4.6 mm) and left ventricular fractional shortening (17.2 +/- 4.6% to 22.7 +/- 7.1%) did not change significantly. One patient died suddenly. These results suggest that 1) some patients with MDCM have neither definite histories nor symptoms to suggest heart failure; 2) the hemodynamic conditions of patients with MDCM do not always deteriorate, but rather stabilize, and even improve during follow-up periods; 3) several types of arrhythmias can be observed, even in standard resting electrocardiograms; and 4) patients with MDCM may die suddenly.
通过心电图和超声心动图对20例轻度扩张型心肌病（MDCM）患者的临床特征进行了研究。MDCM定义为具备以下条件：1）左心室舒张末期内径在55至65毫米之间；2）左心室缩短分数在10%至25%之间。9例患者（45%）无充血性心力衰竭病史。8例患者发生心房颤动，其他12例患者为窦性心律。2例患者有室上性早搏，5例患者有室性早搏。1例患者有阵发性房性心动过速。在这项超声心动图研究的40个月期间，左心室舒张末期内径（从60.8±3.8毫米至57.3±4.6毫米）和左心室缩短分数（从17.2±4.6%至22.7±7.1%）没有显著变化。1例患者突然死亡。这些结果表明：1）一些MDCM患者既无明确的心力衰竭病史，也无提示心力衰竭的症状；2）MDCM患者的血流动力学状况并非总是恶化，而是在随访期间趋于稳定，甚至改善；3）即使在标准静息心电图中也可观察到几种类型的心律失常；4）MDCM患者可能会突然死亡。
