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[心房颤动复律对扩张型心肌病左心室功能的影响。一项多中心研究]

[Effect of cardioversion of atrial fibrillation on left ventricular function in dilated cardiomyopathy. A multicenter study].

作者信息

Sacrez A, Kieny J R, Bouhour J B, Komajda M, Bareiss P, Bouilland H, Ferrière M

机构信息

Service de cardiologie, hôpital de Hautepierre, Strasbourg.

出版信息

Arch Mal Coeur Vaiss. 1990 Jan;83(1):15-21.

PMID:2106301
Abstract

A group of 73 patients with idiopathic dilated cardiomyopathy were followed up for an average of 22 +/- 7 months to assess the medium term evolution of echocardiographic parameters of left ventricular function and, in particular, the consequences of cardioversion of atrial fibrillation. Seventy nine per cent of patients presented with cardiac failure. Left bundle branch block was observed in 20% and ventricular arrhythmias were frequent in 31%, complex in 62% with episodes of non-sustained ventricular tachycardia in 10% of cases. Left ventricular dilatation was greater in patients with complete left bundle branch block (p less than 0.003). Atrial fibrillation was present in 14 patients (19%) who were generally older than the rest of the study population (p less than 0.02) and was associated with less severe left ventricular dysfunction (p less than 0.01). Return to sinus rhythm was obtained in 9 patients. Echocardiographic data was obtained in 64 patients after an average of 6.2 +/- 1.7 months. Left ventricular function improved during the follow-up period and returned to normal in 12% of cases. Reduction of atrial fibrillation to sinus rhythm was the only predictive factor of normalisation of left ventricular function (p less than 0.02). The changes in left ventricular end diastolic dimension and fractional shortening was less marked in the group of 56 patients in sinus rhythm or chronic atrial fibrillation (normalisation of left ventricular function in 8% of cases) than in the group of 8 patients in which atrial fibrillation was converted to sinus rhythm (normalisation of left ventricular function in 50% of cases).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

对73例特发性扩张型心肌病患者进行了平均22±7个月的随访,以评估左心室功能超声心动图参数的中期演变,尤其是房颤复律的后果。79%的患者出现心力衰竭。20%的患者观察到左束支传导阻滞,31%的患者频发室性心律失常,62%为复杂性室性心律失常,10%的病例出现非持续性室性心动过速。完全性左束支传导阻滞患者的左心室扩张更明显(p<0.003)。14例患者(19%)存在房颤,这些患者通常比研究人群的其他患者年龄更大(p<0.02),且与较轻的左心室功能障碍相关(p<0.01)。9例患者恢复窦性心律。平均6.2±1.7个月后,64例患者获得了超声心动图数据。随访期间左心室功能改善,12%的病例恢复正常。房颤转复为窦性心律是左心室功能恢复正常的唯一预测因素(p<0.02)。窦性心律或慢性房颤的56例患者组(8%的病例左心室功能恢复正常)左心室舒张末期内径和缩短分数的变化不如房颤转复为窦性心律的8例患者组(50%的病例左心室功能恢复正常)明显。(摘要截断于250字)

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