Am J Obstet Gynecol. 1990 Nov;163(5 Pt 1):1691-712. doi: 10.1016/0002-9378(90)90653-o.
This consensus report focuses the presentation, pathophysiology, and management of the hypertensive disorders of pregnancy expanding on recommendations first presented in 1988 by the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure. Practicing physicians should determine whether a patient's hypertension during pregnancy falls into the classification of (1) chronic hypertension, (2) preeclampsia, (3) preeclampsia superimposed on chronic hypertension, or (4) transient hypertension. The distinction, for management considerations, is made between hypertension that is present before pregnancy (chronic and preexisting) and that occurring as part of the pregnancy-specific condition preeclampsia. When maternal blood pressure reaches diastolic levels of 100 mm Hg or greater, treatment should be instituted to avoid hypertensive vascular damage. The report includes a discussion of antihypertensive therapy specific to the chronic or acute hypertension occurring concomitantly with pregnancy. The roles of calcium supplementation and low-dose aspirin to prevent preeclampsia and chronic and transient hypertension are under investigation.
本共识报告重点阐述了妊娠期高血压疾病的临床表现、病理生理学及管理,对美国国家高血压检测、评估与治疗联合委员会于1988年首次提出的建议进行了扩展。执业医师应确定患者孕期高血压属于以下哪种分类:(1)慢性高血压;(2)先兆子痫;(3)慢性高血压并发先兆子痫;或(4)短暂性高血压。出于管理考虑,需区分妊娠前就已存在的高血压(慢性且既往存在)和作为妊娠期特有的先兆子痫一部分而出现的高血压。当孕妇舒张压达到或高于100 mmHg时,应进行治疗以避免高血压性血管损伤。该报告讨论了与妊娠同时发生的慢性或急性高血压的降压治疗。补充钙剂和低剂量阿司匹林预防先兆子痫以及慢性和短暂性高血压的作用正在研究中。