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16例卵巢硬化性间质瘤的形态学及免疫组化特征

The morphologic and immunohistochemical spectrum of 16 cases of sclerosing stromal tumor of the ovary.

作者信息

Qureshi Asim, Raza Azizunissa, Kayani Naila

机构信息

Aga Khan Medical University, Karachi, Pakistan.

出版信息

Indian J Pathol Microbiol. 2010 Oct-Dec;53(4):658-60. doi: 10.4103/0377-4929.72017.

DOI:10.4103/0377-4929.72017
PMID:21045387
Abstract

BACKGROUND

Sex-cord-stromal tumors of the ovary are rare neoplasms and they differ from the common surface epithelial tumors in clinical and imaging features.

PATIENTS AND METHODS

This study was done to evaluate the morphologic and immunohistochemical pattern of 16 cases of sclerosing stromal tumor of the ovary diagnosed at a tertiary care hospital. All patients having sclerosing stromal tumor of the ovary were included with the help of medical records using the SNOMED coding system over 10 year period i.e. 1998 to 2008.

RESULT

Sixteen cases of the stromal tumor of the ovary were diagnosed over this 10 year period; the age range was 23 to 40 years (median age 28). In 7 out of 16 cases, serum CA 125 level was done which was raised as per the available medical records. All of these cases showed unilateral. The gross appearance of all the tumors was similar and all had unilateral involvement. Mucin was negative in all of these cases.

摘要

背景

卵巢性索间质肿瘤是罕见的肿瘤,在临床和影像学特征上与常见的表面上皮性肿瘤不同。

患者与方法

本研究旨在评估一家三级医院诊断的16例卵巢硬化性间质瘤的形态学和免疫组化模式。在10年期间(即1998年至2008年),借助使用SNOMED编码系统的病历记录,纳入了所有患有卵巢硬化性间质瘤的患者。

结果

在这10年期间诊断出16例卵巢间质瘤;年龄范围为23至40岁(中位年龄28岁)。16例中有7例检测了血清CA 125水平,根据现有病历记录其水平升高。所有这些病例均为单侧发病。所有肿瘤的大体外观相似,均为单侧受累。所有这些病例中黏液均为阴性。

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The morphologic and immunohistochemical spectrum of 16 cases of sclerosing stromal tumor of the ovary.16例卵巢硬化性间质瘤的形态学及免疫组化特征
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