Kapoor V K
G. H. G. Khalsa College of Pharmacy, Gurusar Sadhar, Ludhiana 141 104, India.
Indian J Exp Biol. 2010 Mar;48(3):228-37.
Plants have been extensively investigated for exploring their therapeutic potentials, but there are comparatively scanty reports on drugs derived from animal kingdom, except for hormones. During last decade, the toxins that are used for defense by the animals, have been isolated and found useful tools for physiological and pharmacological studies, besides giving valuable leads to drug development. Toxins with interesting results have been isolated from the venoms of snakes, scorpions, spiders, snails, lizards, frogs and fish. The present review describe about some toxins as drugs and their biological activities. Some fungal, bacterial and marine toxins have also been covered in this article.
人们已对植物进行了广泛研究以探索其治疗潜力,但除激素外,关于来自动物界的药物的报道相对较少。在过去十年中,动物用于防御的毒素已被分离出来,发现它们不仅为药物开发提供了有价值的线索,还是生理和药理研究的有用工具。从蛇、蝎子、蜘蛛、蜗牛、蜥蜴、青蛙和鱼的毒液中已分离出具有有趣结果的毒素。本综述描述了一些作为药物的毒素及其生物活性。本文还涵盖了一些真菌、细菌和海洋毒素。