University Medical Centre Hamburg-Eppendorf, Department of Psychiatry and Psychotherapy, Hamburg, Germany.
Subst Use Misuse. 2011;46(6):705-15. doi: 10.3109/10826084.2010.509854. Epub 2010 Nov 3.
Studies indicate that different areas of mental, physical, social and daily life functioning need to be considered in order to improve intervention outcomes in substance user patients. The aim of the study was to assess health-related quality of life (HRQOL) in patients diagnosed with opioid dependence as compared to healthy controls and patients diagnosed with depression and schizophrenia.
A total of 1,015 outpatients diagnosed with opioid dependence were investigated during 12 months of maintenance treatment. HRQOL (MSQoL), addiction (EUROP-ASI), and sociodemographic characteristics were assessed.
HRQOL in opioid dependence improved significantly (p < .001), but was lower as compared to that of healthy controls and patients diagnosed with schizophrenia. HRQOL in opioid dependence comprises addiction-specific aspects, most importantly low material satisfaction, physical health, and social stability.
HRQOL measurement provides valuable information for course and outcome in opioid dependence treatment.
研究表明，为了改善物质使用者患者的干预效果，需要考虑心理、生理、社会和日常生活功能的不同领域。本研究旨在评估诊断为阿片类药物依赖的患者的健康相关生活质量（HRQOL）与健康对照组和诊断为抑郁症和精神分裂症的患者相比的情况。
在 12 个月的维持治疗期间，对 1015 名被诊断为阿片类药物依赖的门诊患者进行了调查。评估了 HRQOL（MSQoL）、成瘾（EUROP-ASI）和社会人口学特征。
阿片类药物依赖患者的 HRQOL 显著改善（p<.001），但与健康对照组和精神分裂症患者相比仍较低。阿片类药物依赖患者的 HRQOL 包含成瘾特异性方面，最重要的是物质满足感低、身体健康和社会稳定性。
HRQOL 测量为阿片类药物依赖治疗的过程和结果提供了有价值的信息。
