机器人辅助腹腔镜卵巢组织移植。
Robotic-assisted laparoscopic ovarian tissue transplantation.
机构信息
Department of Obstetrics and Gynecology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
出版信息
Fertil Steril. 2011 Mar 1;95(3):1120.e5-8. doi: 10.1016/j.fertnstert.2010.09.039. Epub 2010 Nov 3.
OBJECTIVE
To describe a technique for frozen-banked ovarian tissue transplantation using robotic-assisted laparoscopy.
DESIGN
Case study.
SETTING
Academic tertiary care center.
PATIENT(S): A 38-year-old patient in remission for non-Hodgkin lymphoma, whose ovarian tissue had been frozen for 3 years.
INTERVENTION(S): Robotic-assisted laparoscopic transplantation of thawed ovarian cortical tissue to the remaining ovary and peritoneum.
MAIN OUTCOME MEASURE(S): Resumption of spontaneous menses, follicular development, and ovulation as demonstrated by ultrasound, and serum E(2) and P levels.
RESULT(S): The patient experienced cyclic spontaneous menstruation 6 months after the transplantation. Ovulation was confirmed by ultrasound and serum E(2) and P levels at month 11 after surgery.
CONCLUSION(S): Robotic-assisted laparoscopic surgery may be a good, minimally invasive alternative for the ovarian tissue transplantation procedure to restore ovarian function.
目的
描述一种使用机器人辅助腹腔镜进行冷冻保存卵巢组织移植的技术。
设计
病例研究。
地点
学术三级保健中心。
患者
一位 38 岁的非霍奇金淋巴瘤缓解期患者，其卵巢组织已冷冻保存 3 年。
干预措施
解冻的卵巢皮质组织的机器人辅助腹腔镜移植到剩余的卵巢和腹膜上。
主要观察指标
超声检查、血清 E2 和 P 水平显示的自发月经恢复、卵泡发育和排卵。
结果
移植后 6 个月，患者出现周期性自发月经。术后 11 个月，通过超声和血清 E2 和 P 水平证实排卵。
结论
机器人辅助腹腔镜手术可能是一种很好的、微创的卵巢组织移植方法，可以恢复卵巢功能。
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