Misumi Ikuo, Chikazawa Shoji, Ishitsu Takateru, Higuchi Shigenori, Shimazu Tomoyuki, Ikeda Chizuru, Uchino Mariko, Shibata Yoshihiro, Ebihara Kenji, Akahoshi Ryuichiro
Department of Cardiology, Kumamoto Saishunsou Hospital, Koushi.
Intern Med. 2010;49(21):2313-6. doi: 10.2169/internalmedicine.49.4210. Epub 2010 Nov 1.
A 39-year-old woman with Sanfilippo C syndrome was referred to our department for the treatment of bradycardia. An electrocardiogram revealed a second degree atrioventricular block, and pacemaker implantation was performed with the patient under general anesthesia. A transthoracic echocardiogram showed normal left ventricular systolic function, moderate mitral regurgitation due to mitral valve prolapse, and a high E/e' ratio, indicating left ventricular diastolic dysfunction. The present patient exhibited a rare case of Sanfilippo syndrome complicated with conduction disturbances, mitral regurgitation, and diastolic dysfunction.
一名患有桑菲利波 C 综合征的 39 岁女性因心动过缓被转诊至我科接受治疗。心电图显示二度房室传导阻滞，遂在全身麻醉下为该患者植入起搏器。经胸超声心动图显示左心室收缩功能正常，因二尖瓣脱垂导致中度二尖瓣反流，且 E/e' 比值升高，提示左心室舒张功能障碍。本例患者为罕见的桑菲利波综合征合并传导障碍、二尖瓣反流及舒张功能障碍病例。
