Al-Qahtani Mashael, Khan Sonia A, Kabiraj Mohammed, Khoja Waleed A
Division of Neurology, Department of Clinical Neurosciences, Riyadh Military Hospital, Riyadh, Kingdom of Saudi Arabia.
Neurosciences (Riyadh). 2009 Jul;14(3):284-6.
Ictal aphasia in adults is a rare phenomenon. Most reported cases manifest with non-fluent (Broca) aphasia. Ictal fluent (Wernicke) aphasia is less common. We report a 47-year-old, right-handed woman that presented with recurrent episodes of non-convulsive seizures in the form of Wernicke's aphasia for 2 weeks. An MRI of the brain showed an old cerebral infarction in the left parieto-occipital area. Scalp EEG revealed continuous periodic sharp waves at the left temporal regions with diffusion to the whole left hemisphere and at occasions to the right. This is followed by variable periods of post ictal slowing. Recurrence of the described ictal pattern was noted. Management of status epilepticus was started in the form of intravenous diazepam and a loading dose of phenytoin and phenobarbitone. After treatment, she improved clinically and the EEG improved with disappearance of the left temporal ictal rhythm and normalization of the EEG background. Thus, establishing the diagnosis of non-convulsive partial status epilepticus manifesting as ictal aphasia.
成人发作性失语是一种罕见现象。大多数报道的病例表现为非流利性(布罗卡)失语。发作性流利性(韦尼克)失语较少见。我们报告一名47岁右利手女性,以韦尼克失语形式出现反复非惊厥性癫痫发作2周。脑部MRI显示左侧顶枕区陈旧性脑梗死。头皮脑电图显示左侧颞区持续周期性尖波,扩散至整个左半球,有时扩散至右侧。随后是发作后不同时长的慢波期。观察到所述发作模式复发。以静脉注射地西泮以及苯妥英和苯巴比妥负荷剂量的形式开始癫痫持续状态的治疗。治疗后,她临床症状改善,脑电图也有所改善,左侧颞区发作性节律消失,脑电图背景恢复正常。从而确诊为表现为发作性失语的非惊厥性部分性癫痫持续状态。