Knight R T, Cooper J
Epilepsia. 1986 May-Jun;27(3):301-4. doi: 10.1111/j.1528-1157.1986.tb03543.x.
Ictal aphasia in adults is a rare phenomenon, with the majority of reported cases showing a nonfluent Broca's or mixed aphasic speech pattern associated with disturbances of level of consciousness. There is usually only one prolonged episode of aphasia with evidence of lateralized neurological findings and structural pathology on CAT scan. We describe a patient with intermittent episodes over a 10-year period of a fluent Wernicke's aphasia associated with paroxysmal posterior temporoparietal spike-wave activity on the EEG. Interictally, the patient was clear of neurologic signs and symptoms. These episodes were repeatedly misdiagnosed as psychotic breaks and treated with antipsychotic medication and psychiatric hospitalization. Unless language performance is assessed, these cases of focal epilepsy may be diagnosed as schizophrenic "word-salad," leading to delay of appropriate treatment.
成人发作性失语是一种罕见现象,大多数报告病例显示为非流利型布罗卡失语或混合性失语的言语模式,并伴有意识水平障碍。通常只有一次长时间的失语发作,计算机断层扫描(CAT)显示有偏侧化神经学表现和结构性病变的证据。我们描述了一名患者,在10年期间出现间歇性发作的流利型韦尼克失语,脑电图显示阵发性后颞顶叶棘波活动。发作间期,患者无神经体征和症状。这些发作多次被误诊为精神病性发作,并接受抗精神病药物治疗和精神科住院治疗。除非评估语言表现,这些局灶性癫痫病例可能被诊断为精神分裂症的“语词杂拌”,从而导致适当治疗的延迟。