Al-Anazi Abdulrahman H, Al-Luwimi Ibrahim M, Shawarby Mohamed A, Mertol Tansu
Department of Neurosurgery, King Fahad Hospital of the University, King Faisal University, PO Box 40010, Al-Khobar 31952, Kingdom of Saudi Arabia. Tel/Fax. +966 (3) 8966743. E-mail:
Neurosciences (Riyadh). 2009 Oct;14(4):371-3.
The co-existence of meningioma and schwannoma as 2 distinct histologic components within the same tumor has been described in neurofibromatosis 2 (NF2), but the co-existence of both tumors without evidence of NF2 is much rarer. Here, we are reporting a case of mixed schwannoma with meningioma without clinical evidence of NF2. In an adult Saudi lady with progressive left-sided hearing loss, left cerebellopontine tumor was diagnosed by MRI, and the histopathological diagnosis revealed that this tumor was composed of vestibular schwannoma and meningioma. This case is discussed with literature review.
在神经纤维瘤病2型（NF2）中，已报道过同一肿瘤内存在脑膜瘤和神经鞘瘤这两种不同组织学成分共存的情况，但在无NF2证据的情况下这两种肿瘤共存则更为罕见。在此，我们报告1例无NF2临床证据的混合性神经鞘瘤伴脑膜瘤病例。在1名患有进行性左侧听力丧失的成年沙特女性中，通过MRI诊断出左侧小脑脑桥角肿瘤，组织病理学诊断显示该肿瘤由前庭神经鞘瘤和脑膜瘤组成。本文结合文献复习对该病例进行了讨论。
