Moss Rehabilitation Research Institute and Thomas Jefferson University, Philadelphia, PA, USA.
Cogn Neuropsychol. 2006;23(1):184-201. doi: 10.1080/02643290500202698.
In the last 20 years, several important developments have markedly expanded our understanding of the hemispatial neglect syndrome and, more broadly, of the brain's representation of objects, space, and action. This review follows seven "threads" of scientific development to evaluate some of the changes in our thinking about the mechanisms of neglect, its key characteristics, the spatial frames of reference affected, the psychophysical properties of neglect phenomena, the relationship of neglect in various sensory modalities, the role of deficits in arousal and general attention, and the critical neuroanatomic substrates of the disorder. The progress reviewed illustrates that the cognitive neuropsychology approach to the study of neglect complements insights gleaned from neurophysiological studies in the monkey, functional neuroimaging studies of attention and perception, and other investigative techniques, and thus serves as fertile ground for a convergence approach to cognitive neuroscience.
在过去的 20 年中,一些重要的进展显著扩展了我们对偏侧空间忽略综合征的理解,更广泛地说,也扩展了我们对大脑对物体、空间和动作的表现的理解。本综述遵循科学发展的七个“线索”,以评估我们对忽略机制、其关键特征、受影响的空间参照系、忽略现象的心理物理学特性、各种感觉模态中忽略的关系、觉醒和一般注意力缺陷的作用以及该疾病的关键神经解剖学基础的思考方式的一些变化。回顾的进展表明,对忽略的认知神经心理学研究方法补充了从猴子的神经生理学研究、注意力和感知的功能神经影像学研究以及其他研究技术中获得的见解,因此为认知神经科学的融合方法提供了肥沃的土壤。