Behavioural Brain Sciences Centre, School of Psychology, University of Birmingham, Birmingham, UK.
Cogn Neuropsychol. 2006 May 1;23(3):463-78. doi: 10.1080/02643290500202755.
We investigated the effects of long-term training using prism adaptation on a patient with chronic neglect. A positive effect of prism adaptation was apparent on tests of visuo-spatial processing (cancellation, bisection, and grasping), but there was no benefit for neglect on the detection of errors on the contralesional side of words or on the detection the left side of chimeric faces. Across training sessions, the benefit of adaptation on immediate performance decreased, but it increased across sessions and within sessions when performance was tested up to 90 minutes after adaptation. The beneficial effect was maintained up to 1 year posttraining. In later sessions there were also increased negative after-effects following prism adaptation, as training progressed. There was no improvement on tests of mathematical cognition, which comprised an independent deficit in this patient. The data suggest that prolonged prism training can induce long-term adaptive spatial realignment of visuo-motor mappings, ameliorating some aspects of neglect. We discuss the implications for the rehabilitation of neglect and for understanding the neglect syndrome more generally.
我们研究了使用棱镜适应进行长期训练对慢性忽视患者的影响。棱镜适应在视空间处理测试（取消、二分法和抓取）中表现出明显的积极效果，但在检测单词对侧的错误或检测嵌合脸的左侧方面，对忽视没有益处。在整个训练过程中，适应的即时表现的益处减少，但在训练期间和训练后 90 分钟内进行测试时，适应的益处增加。这种有益的效果在训练后 1 年仍然保持。在后期的训练中，随着训练的进行，棱镜适应后也会出现更大的负后效。在数学认知测试中没有改善，这在该患者中是一个独立的缺陷。数据表明，长期的棱镜训练可以诱导视动映射的长期适应性空间重新调整，改善忽视的某些方面。我们讨论了忽视康复的意义，以及更广泛地理解忽视综合征的意义。
