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因移植冷冻保存的卵巢组织而怀孕的合法终止。

Legal termination of a pregnancy resulting from transplanted cryopreserved ovarian tissue.

机构信息

Laboratory of Reproductive Biology, The Juliane Marie Centre for Women, Children and Reproduction, Copenhagen University Hospital, Copenhagen University, Denmark.

出版信息

Acta Obstet Gynecol Scand. 2010 Dec;89(12):1589-91. doi: 10.3109/00016349.2010.512074. Epub 2010 Nov 5.

Abstract

Cryopreservation of ovarian tissue is a promising new technique for fertility preservation in patients facing gonadotoxic treatment. Ovarian tissue is extracted and cryo-stored at low temperature prior to treatment. If the woman becomes menopausal, the tissue can be transplanted and a few months later the woman will start to ovulate and be able to conceive, naturally or with assisted reproduction treatment. Currently, 12 healthy children have been born worldwide as a result of transplanting frozen/thawed ovarian tissue. Of these children 3 are Danish and a number of other Danish women are currently attempting to become pregnant. One of these women conceived naturally and had a normal intrauterine pregnancy following transplantation of cryopreserved ovarian tissue. However, the woman decided to terminate the pregnancy within the legal time frame. This pregnancy imposes cryopreservation of ovarian tissue for fertility preservation as a valid method and illustrates that personal life circumstances may rapidly change.

摘要

卵巢组织冷冻保存是一种有前途的生育力保存新技术,适用于面临性腺毒性治疗的患者。在治疗前,将卵巢组织提取并低温冷冻储存。如果女性进入绝经期,可以进行组织移植,几个月后,女性将开始排卵并能够自然或通过辅助生殖治疗怀孕。目前,全世界已经有 12 名健康的儿童通过移植冷冻/解冻的卵巢组织出生。其中 3 名是丹麦儿童,目前还有一些丹麦女性正在尝试怀孕。其中一位女性自然受孕,并在移植冷冻卵巢组织后成功宫内妊娠。然而,该女性在法律规定的时间范围内决定终止妊娠。这一案例证明了卵巢组织冷冻保存作为一种有效的生育力保存方法,同时也说明个人生活状况可能会迅速改变。

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