Department of Gynecology and Obstetrics, Aarhus University Hospital, Aarhus, Denmark.
Hum Reprod. 2010 May;25(5):1280-1. doi: 10.1093/humrep/deq033. Epub 2010 Feb 19.
Worldwide eight children have been born as a result of transplanting frozen/thawed ovarian tissue. Two of these children were born in Denmark following transport of the ovarian tissue for a period of 5 h prior to cryopreservation. One of these women, who was originally transplanted with six pieces of ovarian cortex, after having experienced a period of menopause has now conceived again following natural conception. She gave birth to a healthy girl on 23 September 2008 and is therefore the first woman in the world to have had two children, from separate pregnancies, born as a result of transplanting frozen/thawed ovarian tissue. This result encourages further development of cryopreservation of ovarian tissue for fertility preservation as a clinical procedure for girls and young women facing gonadotoxic treatment.
全世界已经有 8 名儿童通过移植冷冻/解冻的卵巢组织而诞生。其中 2 名儿童是在丹麦诞生的，这些卵巢组织在冷冻前经过了 5 小时的运输。其中一名妇女最初移植了 6 块卵巢皮质，经历了一段更年期后，现在又自然受孕了。她于 2008 年 9 月 23 日生下了一个健康的女孩，因此成为世界上第一个通过移植冷冻/解冻卵巢组织而生育两个孩子（两次怀孕）的女性。这一结果鼓励进一步开发卵巢组织的冷冻保存技术，将其作为面临性腺毒性治疗的女孩和年轻女性的生育力保存的临床程序。
