Zhang Yan, Tang Jie, Li Yan-mi, Fei Xiang, He En-hui, Gao Yuan
Department of Ultrasound, Chinese PLA General Hospital, Beijing 100853, China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2010 Oct;32(5):549-52. doi: 10.3881/j.issn.1000-503X.2010.05.015.
To investigate the value of strain index (SI) by transrectal real-time tissue elastography (TRTE) for differentiation of the prostate peripheral zone lesions.
Totally 83 patients with suspected prostate cancer underwent the quantitative analysis by TRTE examination. The SI of total lesions (ASI) and peak elasticity in lesion (PSI) were calculated, and the pathologic findings were compared. Then the values of ASI and PSI in the differential diagnosis of prostate lesions were assessed. The influence of Gleanson scores on SI was evaluated.
The area under the Receiver Operating Characteristic curves (or ROC curves) of ASI and PSI were 0.62 (P=0.06) and 0.92 (P=0.00) respectively for the differential diagnosis of prostate peripheral lesions. When a cutoff point of 17.44 was used,PSI had a sensitivity of 74.5% and a specificity of 83.3%. Gleason scores showed no significant difference between PSIü 17.44 group and PSIþ17.44 group ( P>0.05).
PSI is helpful for the differential diagnosis of prostate peripheral zone lesions.
探讨经直肠实时组织弹性成像（TRTE）应变指数（SI）在前列腺外周带病变鉴别诊断中的价值。
对83例疑似前列腺癌患者进行TRTE检查定量分析。计算病变总体应变指数（ASI）及病变内弹性峰值（PSI），并与病理结果进行比较。然后评估ASI和PSI在前列腺病变鉴别诊断中的价值。评估Gleason评分对SI的影响。
在前列腺外周带病变的鉴别诊断中，ASI和PSI的受试者操作特征曲线（ROC曲线）下面积分别为0.62（P=0.06）和0.92（P=0.00）。当截断点为17.44时，PSI的敏感度为74.5%，特异度为83.3%。PSI≤17.44组与PSI＞17.44组Gleason评分差异无统计学意义（P＞0.05）。
PSI有助于前列腺外周带病变的鉴别诊断。
